Omeros Corporation

Sr. Accountant The Senior Accountant II will be responsible for developing, implementing and/or maintaining processes within the Company's accounting system and assisting management with primary accounting and reporting functions. Good things are happening at Omeros! Come join our Omeros Accounting Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Responsible for various month end closing activities, including preparing and reviewing significant accrual calculations, non-cash journal entries and reconciliations Prepares stock-based compensation journal entries, reviewing key valuation assumptions for input into our cloud-based equity tracking application Drafts technical accounting memos relating to significant transactions for review by management Assists in drafting the 10-Q and 10-K SEC filings Assists in preparation of Sarbanes-Oxley (SOX) requirements, including the performance and documentation of key control activities Participates in the development and implementation of significant accounting processes and policies to maximize the functionality of Oracle Fusion ERP system Acts as liaison to Omeros business units by providing support and gathering information relating to significant accounting functions Provides audit support, assists with applicable government reporting and participates in other projects as required What education and experience do you need? Bachelor's degree in Business with an accounting concentration Minimum of 5 - 8 years of experience specific to position responsibilities for a Sr. Accountant and 8 - 12 years of experience for a Sr. Accountant II Knowledge of GAAP with experience implementing and documenting internal controls under SOX CPA or CPA candidate with Big 4 public accounting experience Advanced knowledge in Excel and analytical tools Experience with Shareworks or Oracle Fusion is a plus Excellent communication skills, both written and verbal Displays strong analytical and problem-solving skills Detail orientation Behavioral Competencies: Must be able to work collaboratively and maintain positive relationships with management, peers, and subordinates Physical Demands Required: Position requires prolonged periods of sitting and constant use of a computer and keyboard If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at

Temporary Accounting Manager Good things are happening at Omeros! Come join our Accounting Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. Essential Duties & Responsibilities: Manages the entire month-end close process, cash management process, and fixed asset accounting for Omeros Manages all accounting accruals for Legal, IT, Infrastructure, Accounting, Finance, HR and Marketing departments Reviews debt, lease, and payroll entries for month-end close Spearheads internal reporting, collaborating closely with FP&A, the Controller and CFO to create internal reporting from Oracle In conjunction with the Controller, coordinates timing of the audit and preparation of workpapers in a timely and accurate manner Supports the preparation of process documents and design of internal controls for management's SOX attestation Drafts and/or reviews technical accounting memos, providing insight to accounting treatment for new contracts and arrangements Prepares supporting documents used in the creation of SEC and other governmental reporting Preparation of federal, state and local documents for creation of tax provision Assists on projects as needed including optimization projects dealing with our financial and accounting system Manages 2 Senior Accountants and a Staff Accountant for all expenses reported as G&A in the external financial statements Behavioral Competencies Required: The ability to build and maintain positive relationships with management, peers, and subordinates Must display strong analytical and problem-solving skills Ability to manage priorities and workflow Attention to detail Supervisory Responsibilities: Carry out supervisory responsibilities in accordance with the organization's policies and applicable laws Responsibilities include interviewing, hiring, and training employees; planning, assigning, and directing work; appraising performance; rewarding and disciplining employees; addressing complaints and resolving issues Physical Demands and Work Environment Required: Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 20 lbs. May encounter prolonged periods of sitting May be required to work outside normal working hours (evenings/weekends) for quarter or year-end close and or special projects Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

Manager, Accounting Good things are happening at Omeros! Come join our Accounting Team! The Accounting Manager, a key member of the Finance team, is responsible for managing the overall close process, for developing, implementing and/or maintaining general ledger accounting SOX controls and for creating and maintaining internal management reports. Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. Essential Duties & Responsibilities: Manages the entire month-end close process, cash management process, and fixed asset accounting for Omeros Manages all accounting accruals for Legal, IT, Infrastructure, Accounting, Finance, HR and Marketing departments Reviews debt, lease, and payroll entries for month-end close Spearheads internal reporting, collaborating closely with FP&A, the Controller and CFO to create internal reporting from Oracle In conjunction with the Controller, coordinates timing of the audit and preparation of workpapers in a timely and accurate manner Supports the preparation of process documents and design of internal controls for management's SOX attestation Drafts and/or reviews technical accounting memos, providing insight to accounting treatment for new contracts and arrangements Prepares supporting documents used in the creation of SEC and other governmental reporting Preparation of federal, state and local documents for creation of tax provision Assists on projects as needed including optimization projects dealing with our financial and accounting system Manages 2 Senior Accountants and a Staff Accountant for all expenses reported as G&A in the external financial statements Education, Experience, Skills, and Knowledge Required: Bachelor's degree in business with Accounting or Finance concentration A minimum of 5 years of public accounting experience and 2 years of private industry; CPA license preferred Prior experience with Oracle Fusion or similar ERP system is a preferred Advanced Excel with an understanding of pivot tables Proficient with Microsoft Word, Outlook, etc. Solid understanding of GAAP Excellent written and verbal communication skills including the ability to effectively communicate clearly and concisely with all levels Strong collaborator and analytical problem-solver Strong interpersonal and leadership skills (coaching, counseling, training and mentoring, etc.) A proactive self-starter Behavioral Competencies Required: The ability to build and maintain positive relationships with management, peers, and subordinates Must display strong analytical and problem-solving skills Ability to manage priorities and workflow Attention to detail Supervisory Responsibilities: Carry out supervisory responsibilities in accordance with the organization's policies and applicable laws Responsibilities include interviewing, hiring, and training employees; planning, assigning, and directing work; appraising performance; rewarding and disciplining employees; addressing complaints and resolving issues Physical Demands and Work Environment Required: Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 20 lbs. May encounter prolonged periods of sitting May be required to work outside normal working hours (evenings/weekends) for quarter or year-end close and or special projects Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

This position includes both a hands-on, laboratory-based role and managing outsourced projects to support formulation development activities of monoclonal antibodies and small molecules. Formulation development activities will include excipient screening and optimization, stability testing and characterization of routes of degradation of proteins in liquid and lyophilized formulations under various stresses. Laboratory activities include buffer and protein solution preparation, pipetting and aseptic operations in a biosafety cabinet. Activities in support of Drug Product manufacturing may be performed, which include mixing studies, process robustness and tech transfer activities. This position may also support small molecule formulation development for early stage exploratory work through preclinical, clinical and commercial stages. Small molecule formulation development will include application of traditional and enabling technologies for bioavailability enhancement, solution/suspension development, powder characterization (flow, compactability, particle sizing, compressibility); tablet process development and scale-up, solubility and dissolution testing. Good things are happening at Omeros! Come join our Omeros CMC Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Design and execute formulation development and stability studies to support various phase-appropriate antibody drug candidates and small molecules Run routine analytical tests such as size exclusion chromatography, sub-visible particle analysis, viscosity, pH, protein concentration, and appearance Design and execute IV compatibility, in-use stability and microbial challenge studies to recommend clinical and commercial dosing strategy Develop fit-for-purpose analytical methods to support biophysical characterization, formulation stability, and compatibility testing Author technical transfer documents to internal and external manufacturing sites and support the process development and manufacturing of clinical drug substances and drug products Author formulation development and compatibility technical documents for internal use and to support regulatory filings Develop solid and liquid oral dosage form products from preclinical to clinical and commercial stage Apply a strong understanding of formulation and process development in scaling up formulations for oral administration Present work at group, departmental, and cross functional meetings BS degree in Life Sciences, Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, Bioengineering or a related field with 5+ years of experience is required or an MS degree with 2 + years of experience is required Experience with formulation development activities for monoclonal antibodies and novel protein-based molecules, IV admixture compatibility, microbial challenge study, or sterile product development and manufacturing is preferred Strong scientific understanding and experience with pharmaceutics, pharmaceutical science, pharmacy, protein chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development or biomolecule product development Hands-on experience and trouble-shooting proficiency with column chromatographic (HPLC/UPLC), or biophysical techniques (such as DLS, CD, FTIR, DSC, AUC, fluorescence, HIAC, MicroFlow Imaging) for protein characterization Strong technical knowledge in solid oral dosage form development and scale-up Experience in developing and performing characterization of drug product formulations in the lab such as flow, particle sizing, surface area and density Demonstrable experience with various pharmaceutical unit operations such as high shear granulation, roller compaction, compression, fluid bed granulation, blending, milling, tableting and coatingDemonstrable technical understanding of various analytical techniques such as powder x-ray diffraction, dissolution, and solubility testing Familiarity with drug product manufacturing and tech transfer support. Collaboration & Teamwork: Demonstrates the ability to relate to employees and management in a cooperative manner that helps others to achieve their best Productivity/Organizing/Planning: Demonstrates ability to meet deadlines, effectively use time, and handle multiple assignments simultaneously Communication Skills: Ability to convey both written and verbal information effectively and efficiently Willingness to Acknowledge Areas for Growth: Understands need for growth and is receptive to constructive feedback Detail-Oriented: Follows precise procedures and demonstrates thoroughness in performing job tasks and assignments Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs. May encounter prolonged periods of sitting or standing This position requires working around hazardous materials If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at

Secures and maintains patent applications to protect the Company's biotechnology inventions, reviews prior art and other patents in connection with opinions, ensures protection of the Company's trade secrets, drafts and reviews technology transfer, licensing, development and commercialization agreements concerning intellectual property, performs intellectual property due diligence, reviews proposed Company publications. Come join our highly talented Legal Counsel Team and help shape the future of Omeros! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. Essential Duties & Responsibilities: Participate in teams with Company research and development personnel to identify and evaluate corporate biotechnology inventions for patentability, and determine optimal strategy for protection Prepare and prosecute patent applications Draft agreements or portions of agreements pertaining to intellectual property, including research agreements, commercialization agreements, technology transfer agreements and licenses Review proposed Company presentations, publications and releases to ensure intellectual property rights are not jeopardized Evaluate Company research and development activities and third-party patents with respect to freedom to operate Review, search and complete due diligence evaluation of acquisition or licensing opportunities Prepares legal opinions and analyses of patents Review significant corporate legal documents and provide input on intellectual property issue Provides other general legal advice and represents the company in matters relating to intellectual property law An advanced degree in a relevant biology field, or equivalent combination of education and scientific experience, with knowledge and understanding of biotechnology required Juris doctorate (JD Degree) Admitted to practice law in at least one state required, with admission in Washington State preferred Admission to practice in front of the USPTO A minimum of 5 years of related patent preparation and prosecution experience in a law firm, corporation and/or USPTO Substantial experience drafting and negotiating agreements for technology transactions involving life sciences assets Ability to understand the science related to the Company's biopharmaceutical research and development programs and to interact as a scientific peer with research and development team members Must have strong English grammar and usage skills, including in verbal and written communications Must display strong analytical and problem-solving skills Detail orientation Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates Integrity Occasional overnight travel may be required Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs. May encounter prolonged periods of sitting or standing This position requires working around hazardous materials This is an opportunity for you to be a key member of a collaborative group contributing your talent and expertise to a company that has an exciting pipeline. If you have the knowledge, skills and experience we are looking for, we'd love to hear from you! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at .

Research Associate II/Sr. Research Associate, Analytical Development This position will support clinical development and commercialization of antibody therapeutics. The Research Associate will bring a strong technical background including development, transfer, and qualification of analytical methods, characterizing physicochemical attributes of therapeutic candidates, developing new and orthogonal methods for extended characterization, and evaluating orthogonal and complimentary technologies to improve throughput. This position will also contribute to tech transfer to clinical and commercial stage CRO's/CMO's and may contribute to managing external CRO's who may develop and implement methods for routine testing and extended characterization. Good things are happening at Omeros! Come join our Omeros CMC Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Analytical method development, testing, transfer, qualification, and validation in a GLP and/or GMP environment Troubleshoot typical method and equipment challenges Write standard test methods, technical reports summarizing analytical data, and qualification / validation reports Participate in cross-functional teams as a representative of the Analytical Development group Assists in trouble-shooting CMC-related problems from CROs / CMOs Assists in investigations involving data generated internally and by CROs / CMOs Ensures laboratory equipment is calibrated and maintained in proper working order to enable compliance with GLP and/or GMP environments Contribute to drafting regulatory submissions Ensures compliance with all applicable regulatory guidelines What education and experience do you need? BS or MS degree in Chemistry, Biochemistry, Biology, Analytical Chemistry, or a related field with a minimum of 5 years of biotechnology and/or pharmaceutical industry experience Experience developing robust HPLC (SEC, RP, peptide map, CEX, etc.) and/or CE-based (CE-SDS, cIEF, icIEF) methods Experience with troubleshooting and optimizing methods Experience with routine lab equipment and methods, including preparing buffers, measuring pH, UV absorbance, quantifying particulates, etc. Strong understanding of technical principles of chromatographic and/or electrophoretic methods Capable of interpreting data and communicating and presenting results to peers and management Demonstrated written and verbal communication skills with peers and management Experience and proficiency with Waters Empower and/or Sciex 32 Karat software is highly desired Experience with technology transfer to third parties is desired Behavioral Competencies: Demonstrated ability to build and maintain positive and collaborative relationships across functional areas and with management Must display strong analytical, problem-solving, and multi-tasking capabilities Detail oriented, proactive, and self-motivated Physical Demands Required: Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs. May encounter prolonged periods of sitting This position requires working with and near hazardous material If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at

Principal Research Associate, Antibody Discovery In this role, the individual will perform multiple roles within the antibody discovery group at Omeros. The primary role will be to participate in the implementation of antibody discovery campaigns using a mouse hybridoma platform. Other roles will include developing and performing immunoassays and other techniques related to the screening, production, purification and characterization of antibodies and other proteins. Good things are happening at Omeros! Come join our Omeros Discovery Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Participate in the planning and implementation of antibody discovery campaigns using a mouse hybridoma platform Develop and perform immunoassays and biochemical or cellular assays in support of antibody discovery campaigns Produce, purify and characterize antibodies and other proteins What education and experience do you need? College degree in Biology, Biochemistry, or a related life sciences field and 8+ years of relevant academic or industrial lab experience Knowledge of immunization practices and strategies (such as dose schedules and adjuvants) that are used in hybridoma and polyclonal antibody development Experience in handling animals (primarily mice) used for immunization and hybridoma development Solid sterile cell culture experience, including generation and maintenance of stably and transiently transfected cell lines In depth experience with generation, culturing and screening of hybridomas Experience with assays to assess in vitro and in vivo pharmacology of biologics Recombinant protein (especially antibody) purification experience Expression and purification of antibodies and recombinant proteins experience Immunoassays and other plate-based assay platforms experience Experience with SDS-PAGE and other common laboratory methods of protein analysis Planning and implementing experiments independently, preparing buffers and chemical solutions Excellent organizational skills and be committed to keeping detailed, meticulous and comprehensive record keeping, including laboratory notebooks and electronic databases Excellent written and verbal skills, strong analytical and problem-solving skills, and effective in communicating scientific ideas to the group Behavioral Competencies Required: Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates Integrity Physical Demands Required: Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs. May encounter prolonged periods of sitting or standing This position requires working around hazardous materials If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person!Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at

We are a growing and dynamic organization seeking a Process Engineer, Upstream to join our CMC organization. This position is responsible for developing and supporting processes for the manufacture of protein-based therapeutics. The individual will work with internal and external resources for the development of these processes and their transfer to clinical and commercial stage manufacturing plants Good things are happening at Omeros! Come join our Omeros Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G protein-coupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Your responsibilities in this position will include: Manage technical relationships with CMOs responsible for manufacturing GMP drug substance for Omeros Develop and scale up cell culture manufacturing processes suitable for both clinical use and commercial sale Responsible for supporting CMC aspects of the Company's drug substances from development through and including manufacturing Tech transfer of manufacturing processes to CMOs Troubleshoot cell culture, fermentation, and/or purification process and equipment challenges Act as Person in Plant (PIP) to oversee process development and manufacturing activities at CMOs (10-20% of time) Author drug substance related regulatory reports and submissions Ensure compliance with all applicable regulatory guidelines Must have the ability to build and maintain positive relationships with management, peers, and subordinates Excellent written and verbal skills required Must have integrity Must display strong analytical and problem-solving skills Attention to detail required BS or MS degree in chemical engineering or a related field or equivalent professional experience A minimum of 5 years of biotechnology and/or pharmaceutical industry experience. More experienced candidates are encouraged to apply Demonstrated knowledge of cell culture protein processing required Demonstrated problem solving capabilities Ability to navigate global regulatory CMC documents required Experience authoring CMC sections of regulatory submissions and participation in discussions with regulatory agencies preferred Participation in PAIs a plus Experience with cGMPs and Validation practices Experience with at least one biotechnology and/or pharmaceutical product launch is highly desirable Experience supporting regulatory inspections is desirable Good communication, managerial, analytical, planning, and organizational skills a must Demonstrated ability to work in a team environment Will aid in the supervision of activities at multiple CMOs. Responsibilities may include planning, assigning, and directing work at CMOs; and resolving problems that arise at CMOs Overnight travel, approximately 20% of the time, is required Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs. May encounter prolonged periods of sitting This position requires working with and near hazardous material If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at .

Good things are happening at Omeros! Come join our CMC Omeros Team! This position is responsible for developing and supporting processes for the manufacture of protein-based therapeutics. The individual will work with internal and external resources for the development of these processes and their transfer to clinical and commercial stage manufacturing plants. Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Manage technical relationships with CMOs responsible for manufacturing GMP drug substance for Omeros Responsible for supporting CMC aspects of the Company's drug substances from development through and including manufacturing Troubleshoot cell culture, fermentation, and/or purification process and equipment challenges Act as Person in Plant (PIP) to oversee process development and manufacturing activities at CMOs (10-20% of time) Author drug substance related reports and CMC sections of regulatory submissions Ensure compliance with all applicable regulatory guidelines BS or MS degree in chemical engineering or a related scientific field A minimum of 10 years of biotechnology and/or pharmaceutical industry experience Demonstrated knowledge of cell culture and downstream protein processing required Demonstrated problem solving capabilities Ability to navigate global regulatory CMC documents required Experience authoring CMC sections of regulatory submissions and participation in discussions with regulatory agencies preferred Participation in PAIs a plus Familiar with cGMPs and Validation practices Experience with at least one biotechnology and/or pharmaceutical product launch is highly desirable Good organizational skills Demonstrated ability to work in a team environment Excellent written and verbal skills The ability to build and maintain positive relationships with management, peers, and subordinates Integrity Displays strong analytical and problem-solving skills The employee is required to travel overnight, up to 20% of the time Will aid in the supervision of activities at multiple CMOs Responsibilities may include planning, assigning, and directing work at CMOs and resolving problems that arise at CMOs May supervise lower level employees Intermittent physical activity including bending, reaching, pushing, pulling, or lifting, up to 20 lbs May encounter prolonged periods of sitting This position requires working with and near hazardous material Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at .

This position performs a wide variety of activities to ensure compliance with applicable GxP and other regulatory requirements. Good things are happening at Omeros! Come work with our Quality Team! Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Provide support to the current Quality Systems for GxP activities Ensure that the changes related to manufacturing are evaluated and implemented to meet GMP and internal standards Manage the supplier/vendor qualification systems in support of GMP activities. Manage internal and external Deviation/CAPA system Provide QA support for validations including reviewing protocols and reports Provide support in eview of specification and test methods Oversee annual quality management review Ensure compliance with training, doc management, plus preparation and review of Standard Operating Procedures University degree in science and over 7 years of experience in pharmaceutical/ biotech Quality Assurance In-depth knowledge of quality systems and how quality systems are designed and operated to satisfy regulatory requirements Working knowledge and experience with GxP regulations as well as industry standards (USP, Ph. Eur., ICH, FDA, EU guidance Experience in change control, deviation management, and supplier/vendor qualification Knowledge of the principles and practices of computer applications including word processing, spreadsheet, database management, and presentation software and internet search engines Excellent written and verbal skills required Must have the ability to build and maintain positive relationships with management, peers, and subordinates Must display strong analytical and problem-solving skills Self-motivated and able to function effectively within team Attention to detail required Occasional overnight travel is required May frequently be performing repetitive movements such as typing on a keypad or using a mouse May climb, bend, reach, push, pull, balance, stoop, kneel, or crouch On occasion must lift and/or move up to 25 pounds If you have the skills, knowledge and experience we are seeking, we'd love to hear from you! Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at .

Head of Investor Relations Good things are happening at Omeros! Come join our Corporate Team! Working closely with the CEO, VP Finance, Legal, and other members of the executive leadership team, this position will strategically plan, develop, manage, coordinate, and execute on a comprehensive and pro-active investor relations initiative focusing on establishing and maintaining awareness and understanding of Omeros and its many programs and value propositions within the investor community (both individual and institutional) regarding corporate goals and objectives, company developments, and financial results. The ideal candidate will play a critical role in fostering relationships with the investment community, helping shape, articulate and manage the investment story of Omeros and convey key messages about the company's innovative drug pipeline and technology, as well as the company's strategy and vision. Who is Omeros? Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G protein-coupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform. What are your job responsibilities? Responds to inquiries and proactively makes calls effectively communicating the company's operational and financial performance, while establishing realistic expectations for future performance Assists in driving the strategy, operating plans, benchmarking, and execution of the IR program Maintains various IR spreadsheets/models for financial analysis of industry and peer performance, including compilation of analyst assumptions and models Assists in the quarterly earnings release process by preparing the earnings release and portions of the 10K/10Q, conference call scripts, Q&As, maintaining an investor deck, and peer earnings analysis Identify, initiate and cultivate new relationships with investors, analysts and other actors in the investment community that are of strategic importance to Omeros and serve to build understanding and support for the company Understanding the perception of Omeros among the investment community, can formulate plans and recommend initiatives to achieve strategic goals in IR Manages IR contacts, assists with investor targeting and facilitates key relationships with investors and sell-side analysts Coordinates company participation in investor events (e.g.. non-deal road shows, investment conferences) Participates in investor meetings Develops and manages the IR calendar Develops presentations (investor deck) for the investment community, preparing and editing as needed Monitor analyst reports, valuation, stock price performance, sell-side ratings, consensus estimates Manages the content on IR portion of the company's website Develop and monitor performance metrics for the investor relations function Responsible for ensuring all IR material is in compliance with applicable Corporate Policies and procedures BS/BA in Finance, Accounting, or Economics, MBA preferred and PhD or MD in a life science 10+ years of experience in operational and strategic finance roles with a minimum of 5 years of Investor Relations experience; biotech and/or pharma experience required Proven track record of developing a positive, long-term relationship with the investment community Comfortable with valuation and modeling techniques used by investors and analysts Demonstrated ability to understand financial data and articulate that data Excellent communication and presentation skills, both written and verbal, with the ability to write SEC documents including 10K and the ability to translate and simplify complex information and explain the science Strong understanding of finance, capital markets and securities regulations Ability to prioritize multiple tasks on very tight deadlines Strong financial and analytical skills in analyzing financial statements Understanding of disclosure laws, SEC and NASDAQ requirements and sound corporate governance practices Thrives in a fast-paced environment that has multiple demands/shifting priorities and rapid change Proficiency in Microsoft Office Ability to cultivate, influence and maintain positive relationships with internal customers and external investors and analysts Ability to work collaboratively with a team Ability to work cross functionally at all levels of the organization Solution oriented, flexible thinker, driver of success Demonstrated problem-solving skills Integrity Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 25 lbs. May encounter prolonged periods of sitting Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes. It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at .