Research Scientist II

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Takeda Development Center Americas, Inc. is seeking a Research Scientist II in Cambridge, MA with the with the following requirements: Doctorate (PhD) degree in Chemical and Biomolecular Engineering or related field. 36 months of related experience. Will accept any level of experience in the following skills. Required Skills: Implement computational modeling to incorporate factors such as affinity, avidity, target shedding, and target turnover into drug candidate optimization; develop ad hoc computational models for designing dose level, dosing frequency, and dosing route in animal studies; Use Phoenix WinNonlin or Simbiology to integrate in vitro and in vivo data to provide quantitative characterization of the PK/PD/safety relationship; and construct mPBPKPD models of mouse and human to facilitate projection of human efficacy/safety profiles and design of clinical protocols.

Apply on-line at and search for Req # R

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