The Research Associate II or III will work within the Animal Studies team to carry out histology studies that support a diverse range of research efforts in accordance with Precision BioSciences goals. The ideal candidate should have confidence with various histological techniques to carry out histochemical, immunohistochemical, and in situ studies for advancing clinical trials within the cell and gene therapy field.
Essential Duties and Responsibilities Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.
This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.
- Perform laboratory experiments including sample preparation and data collection using established protocols
- Prepare sections of tissue for microscopic examination, using techniques to dissect tissue; embed and orient in paraffin block, cut thin sections of tissue, mount onto glass slides, and stain for features of interest
- Operate computerized instrumentation for tissue dehydration, section clearing, impregnation with paraffin, cutting tissue sections, and staining of slides
- Perform recuts and additional stains, including immunohistochemistry and other specialized stains as needed
- Carry out studies involving histochemical, immunohistochemical, and in situ experiments
- Assist with assay development and optimization
- Perform imaging analysis
- Assist, when needed, with PBS and formalin perfusion, fixation, tissue harvesting, and other tasks as deemed necessary
- May label containers, cassettes and/or slides and affixes coverslips to slides
- Maintain laboratory equipment and tracks all routine maintenance and quality controls performed
- Dispose of hazardous chemical wastes per regulatory guidelines
- Review journals, abstracts and scientific literature to keep up with new developments, procedures, and techniques
Qualifications The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.
Education/ Experience:
- Successful candidate should have a BS in life sciences and 2+ years of relevant histology experience; or equivalent combination of education and experience
Required:
- Ability to work with hazardous chemicals and knowledge of safety requirements to provide instructions and recognize and correct hazardous conditions
- Demonstrated skill in performing a full range of histology applications and operating a variety of laboratory instrumentation
- Experience with In Situ Hybridization (ISH) and Immunohistochemistry (IHC) techniques
- Ability to establish and maintain positive relationships with employees, vendors and external agencies
- Ability to identify and resolve problems as well as communicate clearly and concisely
- The ability to work successfully both independently and in a collaborative environment
- Ability to handle multiple tasks and prioritize effectively
Preferred:
- Cell/gene therapy experience is a plus
Location - This is a laboratory-based position located out of Precision BioSciences main campus in Durham, NC
Travel Requirements - Minimal local travel may be expected for this position. If needed, the Research Associate II-III will be required, on occasion, to travel locally between Precision BioSciences main campus and animal facility in Durham, NC
Precision BioSciences, Inc. (Nasdaq: DTIL), is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS genome editing platform. This isnt just a statement supporting the products that were developing its a statement that speaks to our collective desire to do our part in improving the lives of those around us. ARCUS is a highly specific and versatile genome editing platform designed with therapeutic safety, delivery, and control in mind. Using ARCUS, Precision is developing allogeneic CAR T and in vivo gene correction therapies for cancer and genetic diseases. Our team includes pioneers in genome editing, leaders in business, and a full staff of talented and committed people who are excited to be a part of medical and scientific breakthroughs. For additional information, please visit www. precisionbiosciences.com
Precision BioSciences actively fosters an inclusive environment to ensure we attract and retain the best talent; we value diversity of life experiences and perspectives; and we encourage innovation in pursuit of our mission. We provide equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.