TSR is a premier National U.S. Staffing company with over 50 years of staffing excellence.
Our client, a leading Pharmaceutical company is hiring a QSP Research Scientist on a contracting basis.
Work Location: Princeton NJ
Summary:
- Will be working on a highly stimulating and collaborative environment with biologists, clinicians, pharmacometricians, translational medicine scientists, and in-house QSP modelers
- Drive development and application of Client QSP Immunology models to facilitate back-translation efforts from internal late development programs
- Function as part of team to develop and rigorously assess the functionality, feasibility, efficiency and validity of new models
- Conduct extensive literature review to identify suitable mechanistic elements, interactions, rate constants and sub-modules for incorporation into larger systems (pharmacodynamic & efficacy) models
- Leverage algorithms for parameter optimization and sensitivity analysis
- Analyze model predictions and identify suitable strategies to resolve issues (whenever occur) pertaining to model performance and inaccuracy
- Network as appropriate with experts in Translational Medicine, Discovery Biology, Clinical Development, and other groups to share learnings that maximize the translational value of QSP modeling
- Participate in internal scientific (QSP-related) discussions
- Build and maintain QSP expertise through a personal track record of publication, attendance/participation in conferences, scientific workshops, etc
Required Skills:
- Ph.D. in Engineering, Mathematics, Bioinformatics, Pharmacometrics, Systems Biology/Pharmacology or a related field with a proven record of productivity as demonstrated by publications and conference presentations
- Excellent understanding of theory, principles and statistical aspects of advanced mathematical modeling and simulation, including numerical methods, parameter estimation/optimization, and ordinary differential equations (ODEs)
- Experience in building, validating and using QSP models or deterministic models of biological pathways/systems to support basic science and/or translational clinical research would be particularly desirable
- Hands-on experience with modeling software like MATLAB is required
- Experience with general programming and data analysis tools/languages such as R would be particularly desirable
- Ability to learn new areas of biological sciences and build on solid foundation of quantitative skills to develop mechanistic disease/pharmacology models
- Good understanding of the basic principles of pharmacokinetics and pharmacodynamics
Please contact me directly if you are interested in learning more about this opportunity or to discuss our referral program if you know anyone that may be interested.
Regards,
Dianne Weiss
Technical Recruiter
- provided by Dice