41 jobs found

At Boston Fusion, we recognize diversity is the catalyst for limitless creativity. As a Principal Research Scientist for Boston Fusion, you will have the opportunity to utilize your knowledge of scientific research and software engineering best practices to contribute and drive research efforts in development of systems core to the success of future Intelligence, Surveillance, and Reconnaissance (ISR) activities. This role will lead technical teams as a Principal Investigator, lead and contribute to proposal efforts, and collaborate with project teams to solve complex technical problems that support national security. Every day, we go above and beyond to solve complex problems, making a difference for our nation. We do this by bringing together smart, curious people with diverse life experiences who collaborate creatively to achieve innovative technological breakthroughs. We are proudly building a work environment where you can bring your authentic self to work. Due to the nature of our project work, we can only consider candidates with a current US Citizenship. Day to Day Responsibilities Lead proposal/business capture teams to shape, write and review proposals Interface with customers, including travel, to shape marketing efforts and effectively communicate technical results Investigate fundamental topics in a scientific field such as signal processing, artificial intelligence, machine learning, data science, physics and/or math Lead teams of two or more Scientists, Engineers, and Programmers, including identifying, assigning, and completing research and development tasks appropriate to each member of the team Provide strategic leadership role in working with a project / proposal team to identify the research approach, hypotheses to be tested, and program milestones to achieve all program objectives Facilitate collaboration in large, complex teams to ensure resulting technology (algorithms, software, frameworks) achieves all research objectives Select, improve, or design computational models Identify relevant research approaches, hypotheses to be tested, and program milestones to achieve all program objectives with project and/or proposal teams Provide scientific, technical and software design support to projects and proposals Design statistically valid experiments to test and validate resulting computational models Provide leadership and guidance in the analysis of results of the experiments using sound scientific principles Design experiments to test and validate computational models Establish and maintain a professional rapport with all project stakeholders (internal and external) Additional project and proposal duties as assigned Additional Responsibilities Occasional travel to attend and present at customer meetings and essential industry conferences Prepare technical briefing materials/summarize technical work and progress of projects Collaborate with company leadership and senior technical staff to conduct proposal research and proposal writing Publish technical reports based on original or improved algorithms created to solve the application challenges Maintain high standards at work, continuously looking for solutions to improve processes and products Develop, maintain, and strengthen partnerships with others inside and outside the organization to achieve Boston Fusion business goals Demonstrate personal accountability, effective work habits, integrity, and ethical behavior that align with Boston Fusion corporate values May perform other duties as required This Job is Right for You if you Have: Masters degree in cognitive sciences, engineering, mathematics, physics, or related field, with 13+ years of experience; PhD with 10+ years of experience Excellent analytical and problem-solving skills Ability to prioritize and manage time effectively Excellent communication, writing and presentation skills Ability to work both collaboratively and independently Demonstrates strong competency in every category and a mastery of at least one category Demonstrated competency in AI/ML, and/or signal processing and/or human-machine systems, and/or cognitive sciences, or social sciences, and/or computer vision, or other technical discipline Experience implementing modeling and analysis techniques, including machine learning and probabilistic modelling etc Understanding of mathematical principles which underlie these modeling methods Experience in implementing algorithms in standard programming languages such as Python, Java, C++ Experience in using sound software development techniques, e.g., testing, documentation, source control Preferred Technical Qualifications Classical applied probabilistic, mathematical, and/or artificial intelligence methods (planning, searching, logic, uncertain knowledge, probabilistic reasoning, natural language processing) Radar signal processing techniques Machine learning frameworks (e.g., Scikit-learn, Tensorflow, PyTorch, Keras) and concepts (e.g., supervised, unsupervised, active, and reinforcement learning; neural networks; generative, discriminative models) Preferred Domain Knowledge Experience applying technology to US Department of Defense and/or Intelligence Community problems, including but not limited to the following: intelligence analysis, command and control, logistics, ISR, information operations, missile defense, operations in the cyber, space, or maritime domains 8+ years of experience in a research leadership role Work Authorization/Security Clearance Requirements U.S. citizenship (REQUIRED) and DoD security clearance (PREFERRED) PI6d617c79ea80-7946

A Snapshot of Your Day We are seeking an exceptional and visionary Principal AI Research Scientist to lead our research efforts in developing next-generation foundation models for power grid & substation applications. As a founding member of our new AI lab, you will play a pivotal role in defining our research agenda, driving innovation in algorithms, architectures, and methodologies for scaling AI models, and building and mentoring a world-class team. You will tackle fundamental research challenges with significant real-world impact, pushing the boundaries of AI to revolutionize the energy landscape and address critical challenges related to grid modernization, renewable energy acceleration and climate change mitigation. This is a hands-on role that demands a strong research background and deep expertise in AI foundation models and ability to develop for creating transformational change. How You'll Make an Impact Conducting original, high-impact research in foundation models, specifically tailored for power grid data modalities and applications, and spearheading the development of novel deep learning architectures, algorithms, and training methodologies tailored for these Deeply investigating and advancing state-of-the-art research in relevant areas, adapting and integrating methods and techniques from public research Collaborating closely with AI engineers and domain experts to translate research breakthroughs into practical, scalable solutions deployable within real-world power grid systems Building and mentoring a high-performing research team, fostering a collaborative and innovative research culture within the newly formed AI lab, and driving rapid iteration and proof-of-concept (PoC) development to quickly validate research ideas Communicating research findings effectively to both technical and non-technical audiences (via technical blogs or publications in conferences and journals), and representing the lab externally at conferences and industry events Driving research projects forward independently, demonstrating strong initiative, problem-solving skills, and a results-oriented approach What You Bring Master's or Ph.D. in Computer Science, Electrical Engineering, Physics, Mathematics, or a related quantitative field 5 or more years of research experience in Deep Learning, Machine Learning, or related areas, with a focus on developing and scaling innovative AI solutions. Candidates with more experience can be considered for a higher level or vice-versa Experience building foundation models and related concepts, with direct prior experience in at least one of the following AI for Simulation/AI for Physics, Neural Operators, GNNs (Graph Neural Networks), Transformers Proven ability to design, develop, and implement novel deep learning architectures and algorithms Experience scaling solutions involving large datasets and complex models, utilizing large compute clusters Strong ability to work independently, rapidly iterate on ideas, and quickly develop and validate proof-of-concepts; Excellent communication, presentation, and teamwork skills, with the ability to lead and inspire a research team and collaborate effectively with diverse stakeholders Preferred qualifications include: Publications in top-tier AI conferences and journals, contributions to open-source machine learning projects, and/or prior experience in a top AI research lab; Experience applying AI/ML to power systems, electrical grids, or related domains About the Team Join Siemens Energy new AI initiative to transform power grids! At our newly established AI Lab with powerful dedicated compute cluster, we are tackling the critical challenge of global grid congestion and revolutionizing antiquated grid operation and planning. We're combining 100 years of energy domain expertise with the latest advancements in AI foundation models for energy applications to fundamentally reshape the future of substations and power grids. The AI Lab will be pioneering innovative and transformational solutions that will be productized and deployed across a large global footprint. This is your chance to drive a new way of thinking in the energy sector and build a more resilient and sustainable energy infrastructure. Who is Siemens Energy? At Siemens Energy, we are more than just an energy technology company. With 100,000 dedicated employees in more than 90 countries, we develop the energy systems of the future, ensuring that the growing energy demand of the global community is met reliably and sustainably. The technologies created in our research departments and factories drive the energy transition and provide the base for one sixth of the world's electricity generation. Our global team is committed to making sustainable, reliable, and affordable energy a reality by pushing the boundaries of what is possible. We uphold a 150-year legacy of innovation that encourages our search for people who will support our focus on decarbonization, new technologies, and energy transformation. Find out how you can make a difference at Siemens Energy: Rewards/Benefits Career growth and development opportunities Supportive work culture Company paid Health and wellness benefits Paid Time Off and paid holidays 401K savings plan with company match Family building benefits and parental leave

A client of Innova Solutions is immediately hiring for a Scientist Principal Position type: Full-time- Contract Duration: 6 Months Location: South San Francisco, CA (Remote) As Scientist Principal, you will: Job Description: Top 3 Must Have Skill Sets: Computational Biology Expertise - Ability to integrate and analyze complex multi-omics datasets (genomics, transcriptomics, proteomics, etc.) to drive biomarker discovery and patient stratification. AI/ML Innovation - Proven skill in applying advanced AI/ML methods in translational and clinical research to generate predictive insights and accelerate biomarker innovation. Oncology Experience - Must have Oncology experience as this will be supporting an Oncology team. Day to Day Responsibilities: Support the development of clinical biomarkers supporting client's programs through the formulation and execution of biomarker data analysis. Perform assessment of biochemical coverage, patient stratification, indication selection in client's early and late clinical development programs and discovery of clinical insights at asset and portfolio levels through the application of knowledge discovery and data mining techniques. Conduct exploratory analysis of clinical trial biomarker/omics data, public/consortium data, and other relevant datasets to uncover novel insights and support clinical programs. Develop translational informatics analysis workflows in a high-content, multi-omics, multi-modal data domain encompassing genomics, transcriptomics, proteomics, metabolomics, and epigenomics domains. Collaborate with oncology biologists and cross-functional partners (DTI, assay labs, biomarker scientists, diagnostics teams) to ensure computational analyses are aligned with biological and clinical goals. Champion and exemplify the application of knowledge graphs and modern AI/ML (including generative and transfer learning techniques and task specialization of foundational models) to enable understanding and prediction of clinical endpoints or adverse events (e.g., ocular toxicity). Represent CfTI in some client's program/portfolio teams as a biomarker analysis lead. Participate in diagnostics assay and vendor evaluation and selection by providing inputs from computational perspective. Interface cross-functionally with the early development teams, assay laboratories, in-vitro diagnostics, and biomarker representatives. Partner with the Reverse Translation Computational Biology lead to support cross-program initiatives. Qualified candidates should APPLY NOW for immediate consideration! Please hit APPLY to provide the required information, and we will be back in touch as soon as possible. We are currently interviewing to fill this and other similar positions. If this role is not a fit for you, we do offer a referral bonus program for referrals that we successfully place with our clients, subject to program guidelines. ASK ME HOW. Thank you! Harish Yadav Phone: PAY RANGE AND BENEFITS: Pay Range : $54.00-$58.00 per hour. Pay range offered to a successful candidate will be based on several factors, including the candidate's education, work experience, work location, specific job duties, certifications, etc. Benefits: Innova Solutions offers benefits( based on eligibility) that include the following: Medical & pharmacy coverage, Dental/vision insurance, 401(k), Health saving account (HSA) and Flexible spending account (FSA), Life Insurance, Pet Insurance, Short term and Long term Disability, Accident & Critical illness coverage, Pre-paid legal & ID theft protection, Sick time, and other types of paid leaves (as required by law), Employee Assistance Program (EAP). ABOUT INNOVA SOLUTIONS: Founded in 1998 and headquartered in Atlanta, Georgia, Innova Solutions employs approximately 50,000 professionals worldwide and reports an annual revenue approaching $3 Billion. Through our global delivery centers across North America, Asia, and Europe, we deliver strategic technology and business transformation solutions to our clients, enabling them to operate as leaders within their fields. Recent Recognitions: Named One of America's Best Employers for New Grads by Forbes (2024 Named One of the Best Companies to Work for by U.S. News & World Report (Private Companies List, ) One of the Largest IT Staffing Firms in the US - Ranked by Staffing Industry Analysts (SIA, 2024) One of the Largest Staffing Firms in the US - Ranked by Staffing Industry Analysts (SIA, 2024; includes Innova Solutions, Volt, & HireGenics) Named One of the Top Ten Private Companies in Atlanta by the Atlanta Business Chronicle (2023) One of the Largest Certified Minority Business Enterprises (MBEs) in the United States (NMSDC, 2024) AWS Advanced Tier Services Partner with 100+ certifications Website: Innova Solutions offers a referral bonus for qualified Ambassadors who refer eligible referrals. Submit referrals at and earn $250-$1,000 per referral. Innova Solutions is an Equal Opportunity Employer and prohibits any kind of unlawful discrimination and harassment. Innova Solutions is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment on the basis of race, color, religion or belief, national origin, citizenship, social or ethnic origin, sex, age, physical or mental disability, veteran status, marital status, domestic partner status, sexual orientation, or any other status protected by the statutes, rules, and regulations in the locations where it operates. If you are an individual with a disability and need a reasonable accommodation to assist with your job search or application for employment, please contact us at or . Please indicate the specifics of the assistance needed. Innova Solutions encourages all interested and qualified candidates to apply for employment opportunities. Innova Solutions (HireGenics/Volt) does not discriminate against applicants based on citizenship status, immigration status, or national origin, in accordance with 8 U.S.C. 1324b. The company will consider for employment qualified applicants with arrest and conviction records in a manner that complies with the San Francisco Fair Chance Ordinance, the Los Angeles Fair Chance Initiative for Hiring Ordinance, and other applicable laws.

At Boston Fusion, we recognize diversity is the catalyst for limitless creativity. As a Principal Research Scientist for Boston Fusion, you will have the opportunity to utilize your knowledge of scientific research and software engineering best practices to contribute and drive research efforts in development of systems core to the success of future Intelligence, Surveillance, and Reconnaissance (ISR) activities. This role will develop new approaches, investigate existing algorithms and models, design and perform scientific analyses, and develop solutions to complex research problems for military and intelligence community customers. Every day, we go above and beyond to solve complex problems, making a difference for our nation. We do this by bringing together smart, curious people with diverse life experiences who collaborate creatively to achieve innovative technological breakthroughs. We are proudly building a work environment where you can bring your authentic self to work. Due to the nature of our project work, we can only consider candidates with current US Citizenship. Day to Day Responsibilities Lead proposal/business capture teams to shape, write and review proposals Interface with customers, including travel, to shape marketing efforts and effectively communicate technical results Investigate fundamental topics in a scientific field such as signal processing, artificial intelligence, machine learning, data science, physics and/or math Lead teams of two or more Scientists, Engineers, and Programmers, including identifying, assigning, and completing research and development tasks appropriate to each member of the team Provide strategic leadership role in working with a project / proposal team to identify the research approach, hypotheses to be tested, and program milestones to achieve all program objectives Facilitate collaboration in large, complex teams to ensure resulting technology (algorithms, software, frameworks) achieves all research objectives Select, improve, or design computational models Identify relevant research approaches, hypotheses to be tested, and program milestones to achieve all program objectives with project and/or proposal teams Provide scientific, technical and software design support to projects and proposals Design statistically valid experiments to test and validate resulting computational models Provide leadership and guidance in the analysis of results of the experiments using sound scientific principles Design experiments to test and validate computational models Establish and maintain a professional rapport with all project stakeholders (internal and external) Additional project and proposal duties as assigned Additional Responsibilities: Occasional travel to attend and present at customer meetings and essential industry conferences Required Education and Experience: Masters degree (13+ years experience) or PhD (10+ years experience) in cognitive sciences, engineering, mathematics, physics, or related field Excellent analytical and problem-solving skills Ability to prioritize and manage time effectively Excellent communication, writing and presentation skills Ability to work both collaboratively and independently Required Technical Qualifications: Demonstrates strong competency in every category and a mastery of at least one category Demonstrated competency in AI/ML, and/or signal processing and/or human-machine systems, and/or cognitive sciences, or social sciences, and/or computer vision, or other technical discipline Experience implementing modeling and analysis techniques, including machine learning and probabilistic modelling etc. Understanding of mathematical principles which underlie these modeling methods. Experience in implementing algorithms in standard programming languages such as Python, Java, C++. Experience in using sound software development techniques, e.g., testing, documentation, source control. Preferred Technical Qualifications: Classical applied probabilistic, mathematical, and/or artificial intelligence methods (planning, searching, logic, uncertain knowledge, probabilistic reasoning, natural language processing) Machine learning frameworks (e.g., PyTorch, Scikit-learn) and concepts (e.g., supervised, unsupervised, active, and reinforcement learning; neural networks; generative, discriminative models) Preferred Domain Knowledge: 5+ years of experience applying technology to US Department of Defense and/or Intelligence Community problems, including but not limited to the following: intelligence analysis, command and control, logistics, ISR, information operations, missile defense, operations in the cyber, space, or maritime domains 10+ years of experience in a research leadership role Work Authorization/Security Clearance Requirements: U.S. citizenship (REQUIRED), DoD security clearance (PREFERRED) PIba925ec5861e-0751

At Boston Fusion, we recognize diversity is the catalyst for limitless creativity. As a Principal Research Scientist for Boston Fusion, you will have the opportunity to utilize your knowledge of scientific research and software engineering best practices to contribute and drive research efforts in development of systems core to the success of future Intelligence, Surveillance, and Reconnaissance (ISR) activities. This role will develop new approaches, investigate existing algorithms and models, design and perform scientific analyses, and develop solutions to complex research problems for military and intelligence community customers. Every day, we go above and beyond to solve complex problems, making a difference for our nation. We do this by bringing together smart, curious people with diverse life experiences who collaborate creatively to achieve innovative technological breakthroughs. We are proudly building a work environment where you can bring your authentic self to work. Due to the nature of our project work, we can only consider candidates with current US Citizenship. Day to Day Responsibilities Lead proposal/business capture teams to shape, write and review proposals Interface with customers, including travel, to shape marketing efforts and effectively communicate technical results Investigate fundamental topics in a scientific field such as signal processing, artificial intelligence, machine learning, data science, physics and/or math Lead teams of two or more Scientists, Engineers, and Programmers, including identifying, assigning, and completing research and development tasks appropriate to each member of the team Provide strategic leadership role in working with a project / proposal team to identify the research approach, hypotheses to be tested, and program milestones to achieve all program objectives Facilitate collaboration in large, complex teams to ensure resulting technology (algorithms, software, frameworks) achieves all research objectives Select, improve, or design computational models Identify relevant research approaches, hypotheses to be tested, and program milestones to achieve all program objectives with project and/or proposal teams Provide scientific, technical and software design support to projects and proposals Design statistically valid experiments to test and validate resulting computational models Provide leadership and guidance in the analysis of results of the experiments using sound scientific principles Design experiments to test and validate computational models Establish and maintain a professional rapport with all project stakeholders (internal and external) Additional project and proposal duties as assigned Additional Responsibilities: Occasional travel to attend and present at customer meetings and essential industry conferences Required Education and Experience: Master's degree (13+ years' experience) or PhD (10+ years' experience) in cognitive sciences, engineering, mathematics, physics, or related field Excellent analytical and problem-solving skills Ability to prioritize and manage time effectively Excellent communication, writing and presentation skills Ability to work both collaboratively and independently Required Technical Qualifications: Demonstrates strong competency in every category and a mastery of at least one category Demonstrated competency in AI/ML, and/or signal processing and/or human-machine systems, and/or cognitive sciences, or social sciences, and/or computer vision, or other technical discipline Experience implementing modeling and analysis techniques, including machine learning and probabilistic modelling etc. Understanding of mathematical principles which underlie these modeling methods. Experience in implementing algorithms in standard programming languages such as Python, Java, C++. Experience in using sound software development techniques, e.g., testing, documentation, source control. Preferred Technical Qualifications: Classical applied probabilistic, mathematical, and/or artificial intelligence methods (planning, searching, logic, uncertain knowledge, probabilistic reasoning, natural language processing) Machine learning frameworks (e.g., PyTorch, Scikit-learn) and concepts (e.g., supervised, unsupervised, active, and reinforcement learning; neural networks; generative, discriminative models) Preferred Domain Knowledge: 5+ years of experience applying technology to US Department of Defense and/or Intelligence Community problems, including but not limited to the following: intelligence analysis, command and control, logistics, ISR, information operations, missile defense, operations in the cyber, space, or maritime domains 10+ years of experience in a research leadership role Work Authorization/Security Clearance Requirements: U.S. citizenship (REQUIRED), DoD security clearance (PREFERRED) PI22835ced5-

At Boston Fusion, we recognize diversity is the catalyst for limitless creativity. As a Principal Research Scientist for Boston Fusion, you will have the opportunity to utilize your knowledge of scientific research and software engineering best practices to contribute and drive research efforts in development of systems core to the success of future Intelligence, Surveillance, and Reconnaissance (ISR) activities. This role will lead technical teams as a Principal Investigator, lead and contribute to proposal efforts, and collaborate with project teams to solve complex technical problems that support national security. Every day, we go above and beyond to solve complex problems, making a difference for our nation. We do this by bringing together smart, curious people with diverse life experiences who collaborate creatively to achieve innovative technological breakthroughs. We are proudly building a work environment where you can bring your authentic self to work. Due to the nature of our project work, we can only consider candidates with a current US Citizenship. Day to Day Responsibilities Lead proposal/business capture teams to shape, write and review proposals Interface with customers, including travel, to shape marketing efforts and effectively communicate technical results Investigate fundamental topics in a scientific field such as signal processing, artificial intelligence, machine learning, data science, physics and/or math Lead teams of two or more Scientists, Engineers, and Programmers, including identifying, assigning, and completing research and development tasks appropriate to each member of the team Provide strategic leadership role in working with a project / proposal team to identify the research approach, hypotheses to be tested, and program milestones to achieve all program objectives Facilitate collaboration in large, complex teams to ensure resulting technology (algorithms, software, frameworks) achieves all research objectives Select, improve, or design computational models Identify relevant research approaches, hypotheses to be tested, and program milestones to achieve all program objectives with project and/or proposal teams Provide scientific, technical and software design support to projects and proposals Design statistically valid experiments to test and validate resulting computational models Provide leadership and guidance in the analysis of results of the experiments using sound scientific principles Design experiments to test and validate computational models Establish and maintain a professional rapport with all project stakeholders (internal and external) Additional project and proposal duties as assigned Additional Responsibilities Occasional travel to attend and present at customer meetings and essential industry conferences Prepare technical briefing materials/summarize technical work and progress of projects Collaborate with company leadership and senior technical staff to conduct proposal research and proposal writing Publish technical reports based on original or improved algorithms created to solve the application challenges Maintain high standards at work, continuously looking for solutions to improve processes and products Develop, maintain, and strengthen partnerships with others inside and outside the organization to achieve Boston Fusion business goals Demonstrate personal accountability, effective work habits, integrity, and ethical behavior that align with Boston Fusion corporate values May perform other duties as required This Job is Right for You if you Have: Master's degree in cognitive sciences, engineering, mathematics, physics, or related field, with 13+ years of experience; PhD with 10+ years of experience Excellent analytical and problem-solving skills Ability to prioritize and manage time effectively Excellent communication, writing and presentation skills Ability to work both collaboratively and independently Demonstrates strong competency in every category and a mastery of at least one category Demonstrated competency in AI/ML, and/or signal processing and/or human-machine systems, and/or cognitive sciences, or social sciences, and/or computer vision, or other technical discipline Experience implementing modeling and analysis techniques, including machine learning and probabilistic modelling etc Understanding of mathematical principles which underlie these modeling methods Experience in implementing algorithms in standard programming languages such as Python, Java, C++ Experience in using sound software development techniques, e.g., testing, documentation, source control Preferred Technical Qualifications Classical applied probabilistic, mathematical, and/or artificial intelligence methods (planning, searching, logic, uncertain knowledge, probabilistic reasoning, natural language processing) Radar signal processing techniques Machine learning frameworks (e.g., Scikit-learn, Tensorflow, PyTorch, Keras) and concepts (e.g., supervised, unsupervised, active, and reinforcement learning; neural networks; generative, discriminative models) Preferred Domain Knowledge Experience applying technology to US Department of Defense and/or Intelligence Community problems, including but not limited to the following: intelligence analysis, command and control, logistics, ISR, information operations, missile defense, operations in the cyber, space, or maritime domains 8+ years of experience in a research leadership role Work Authorization/Security Clearance Requirements U.S. citizenship (REQUIRED) and DoD security clearance (PREFERRED) PI7bdb527a781e-7946

_SENIOR STUDY DIRECTOR/ TOXICOLOGIST_ _PRECLINICAL/ NONCLINICAL DRUG DEVELOPMENT_ We are a growing mid-size organization with multiple sites looking for an accomplished Senior Study Director for our Toxicology division to assist with the growth we are experiencing and have plans to continue. Say Goodbye to the bureaucracy and the administrative aspects of large cumbersome organizations and say _Hello to the Science_! As a Senior Study Director, you will be responsible for participating in the design of non-clinical / preclinical in vivo studies as well as providing the scientific oversight of the study. The study director will direct and participate in the planning, organization, conduct and interpretation of animal research according to the regulations, protocols, standards and guidelines such as USDA, FDA, GLP, GCP, etc. Be responsible for monitoring studies and providing updates to both client sponsors and senior management. Ensure that the employees are performing the study according to protocols and Standard Operating Procedures (SOPs) These studies will involve standard laboratory animal species (mice, rats, NHP, swine) across typical test article types (Vaccines, Bio-pharmaceuticals, Small Molecules). This role will encompass multiple site studies and coordination thereof. * Serve as Study Director and participate in research projects including protocol development, preparation and administration of test article, collecting and processing samples or tissues from subjects. * Plan an outline of research procedures to be followed during the course of the experiment. Writing protocols and reports as well as reviewing study schedules. * Communicate with clients regularly regarding updates, amendments, deviations, study results etc. * Assist in ensuring that personnel allocated to performing research activities for their studies have a clear understanding of the research protocol, activities to be performed, and are properly trained to conduct the procedures. * Maintaining and completing multiple projects simultaneously * Developing Protocols * Communicating with staff, management, and clients/sponsors * Analysis, interpretation, and reporting of data from non-clinical studies. * Manage the conduct of study activities in compliance with the protocol, amendments, and facility SOPs * May also assist in the further development of SOPs, training materials, and policies. * Proactive recognition, documentation, and resolution of any issues affecting the conduct of non-clinical studies. * Maintain knowledge of FDA and other regulatory guidelines * Work with the appropriate individuals to design and approve the study protocols * Perform other duties directed by the Director of Toxicology to meet client needs. * Develop and Maintan SOPs, assist in developing training materials as needed, mentor junior Study Directors [SENIOR STUDY DIRECTOR AND PRINCIPAL STUDY DIRECTOR] * Provide Input on company policies, procedures, and documentation necessary to maintain compliance with the GLP guidelines and to ensure scientific rigor in the studies conducted on site [PRINCIPAL STUDY DIRECTOR] EXPERIENCE, EDUCATION, AND SPECIALIZED KNOWLEDGE AND SKILLS: _Study Director_ * Education and Experience * BS/BA in a relevant scientific field with 2 -4 years experience - OR - Masters Degree in a relevant scientific field with 2 years experience _Senior Study Director_ * Education and Experience * BS/BA in a relevant scientific field with 6-8 years of related drug development experience - OR - PhD in a relevant scientific field with 4 years related experience _Principal Scientist - Principal Study Director_ * Education and Experience * BS/BA in a relevant scientific field with 16 years of related drug development experience - OR - PhD in a relevant scientific field with 12 years related experience This role will offer relocation and will also offer partial Work From Home ability (cannot work remote from another state) DABT or Board eligible preferred Essential Skills include: leadership, good organizational skills, knowledge of an experience with GLP (Good Laboratory Practices), AAALAC and USDA guidelines, experience using computer applications.

RESEARCH SCIENTIST/STUDY DIRECTOR OCULAR DESCRIPTION: We are seeking to find an accomplished Ocular Scientist with requirements of a broad knowledge of Ocular anatomy, physiology, and biochemistry to help develop and support in vivo models to screen small molecule, cell/gene therapy, as well as large molecule therapeutics and devices being developed for various ocular disorders. Experience with ocular surgical, dosing and sampling techniques is necessary. The Ocular Research Scientist will assist in the development of protocols and criteria to effectively and efficiently carry out experiments. The successful candidate will provide investigators with written and oral updates to scientific data generated during the conduct of the studies they oversee. They may also participate in presentations at scientific meetings and/or preparation of manuscripts for presentations. Expertise to guide investigators on the approaches necessary to characterize the pharmacological effects of target molecules based on disease mechanisms is valuable. PRINCIPAL DUTIES AND RESPONSIBILITIES: The Scientist will perform the following duties and responsibilities: * Assume the functional role of Principal Investigator or Study Director for preclinical ophthalmic studies. * Participate in study design and the development and generation of study protocols. * Manage the conduct of preclinical studies, evaluated the data, and assist in the writing and review of final reports. * Develop and execute research studies to expand research capabilities. * Develop and execute training programs for research associates and junior team members. * Write or revise Standard Operating Procedures (SOPs) to assure facility compliance with applicable regulations, client expectations, and current industry standards. * May be asked to serve on the Institutional Animal Care and Use Committee (IACUC) REQUIREMENTS: * Hands-on in vivo experience with multiple research species, at a minimum, rodent, and rabbit. * Ability to perform ocular injections, such as sub-conjunctival, sub-tendon, retrobulbar, intravitreal, and/or subretinal injections. * Experience with various imaging modalities, such as Optical coherence tomography (OCT), fundus photography, and fluorescein angiography. * Experience with other ocular techniques, such as intraocular pressure measurements, electroretinography (ERG), or optokinetic response (OKR). * Ability to perform duties and responsibilities with minimal supervision * Ability to understand Standard Operating Procedures (SOPs) and study protocols. * Must be flexible to work various schedules and hours as well as provide comprehensive, after-hours, and on-call coverage as needed. EDUCATION * Graduate-level degree (M.S./ PhD/ DVM, VMD) required. Post Doctoral candidates are preferred. * Additional training in the GLPs and other applicable regulations required. EXPERIENCE * Minimum 3-6 years of experience required, based on education.

Overview / Responsibilities Wood Environment & Infrastructure Solutions is currently seeking an Environmental Scientist / Geologist / Engineer to join our team in Blue Bell, PA or Hamilton, NJ. Are you a Scientist, Geologist or Engineer with 1 to 4 years of environmental experience? Are you looking for an opportunity to work with Senior Staff on a variety of technically challenging environmental projects? Are you looking for an opportunity to work with an established environmental consulting firm that values its employee's enthusiasm and technical contributions? We encourage you to apply for this opportunity. We are dedicated to providing the atmosphere to allow individuals to grow their career. Key Responsibilities : This individual will be approximately 80% in the field on industrial sites and 20% in the office Will work under the supervision of a Principal Scientist Field activities include soil borings, groundwater monitoring well installations and collecting soil, groundwater, surface water and sediment samples as well as documenting field activities Field activities may also include oversight of remediation subcontractors during remediation activities including pilot studies and remediation system installation Acts as a data gatherer; prepares maps, charts; runs simple computer programs Performs field testing; uses equipment and instrumentation Interprets data and test results, with experience and may write complete reports Prepares field reports, internal correspondence, sections of formal reports Follows company safety standards, site safety standards and provides all required permitting Contacts vendors; researches literature and regulatory requirements; prepares draft designs Conducts engineering or scientific calculations; coordinates geometry; performs minimal design work, preliminary analysis and layout Skills / Qualifications Required : BS or MS in Environmental Science, Geology, Environmental Engineering or related technical field 1 to 4 years environmental experience EIT for engineers preferred Must be a self-starter with excellent written and verbal communication skills Strong computer skills for database work and proficiency in MS Office Flexible to work outside normal business hours as required Willingness to travel to project sites in the New Jersey, New York and Pennsylvania area with overnight travel Must pass drug test, physical, background check and must have a satisfactory driving record in accordance with the company's driving (MVR) policy Preferred : OSHA 40 hour certification Physical Demands : Field activities may require working in unfavorable weather conditions Field activities may require working in specialized protective equipment supplied by employer. Candidate must be physically capable of performing tasks in such equipment Will lift equipment and carry laboratory samples which requires the ability to lift 40 pounds Company Overview Wood is a global leader in engineering and consultancy across energy and the built environment, helping to unlock solutions to some of the world's most critical challenges. We provide consulting, projects and operations solutions in more than 60 countries, employing around 45,000 people. Diversity Statement We are an equal opportunity employer that recognises the value of a diverse workforce. All suitably qualified applicants will receive consideration for employment on the basis of objective criteria and without regard to the following (which is a non-exhaustive list): race, colour, age, religion, gender, national origin, disability, sexual orientation, gender identity, protected veteran status, or other characteristics in accordance with the relevant governing laws.

Category:Administration Lab/Area:GrantsDescription: The Gladstone Institutes is seeking an experienced Pre-Award Grants Administrator to join its Grants and Contracts Department on a temporary, full-time basis through December 2021. This position is fully remote, working West Coast business hours. This position will provide direct support to Gladstone's principal investigators in all aspects of pre-award research administration. From day one, the successful candidate will be a trusted partner to Gladstone scientists throughout the proposal development process, and will work cross-functionally with scientific and administrative teams to provide excellent service and generate high-quality deliverables. They will be comfortable managing competing deadlines and working with diverse constituents in a fast-paced research environment. The successful candidate will: Own the pre-award process from idea to award, working in close partnership with principal investigators and staff scientists to move proposals through the pipeline. Track application deadlines and manage time accordingly. Ensure proposals conform to sponsor regulations and requirements. Develop budgets and administrative documentation for outgoing proposals. Ensure compliance with internal review and approval processes. Submit research proposals to sponsors. Negotiate acceptable award terms. Review awards for compliance and audit issues. Assist with identifying potential funding sources. Process non-competing continuations, progress reports, supplements, subaward requests, research agreements and all other award and agreement amendments. Coordinate Just-In-Time submissions for probable awards. Complete award setup in the accounting system. Perform data entry in proposal and award tracking system. Generate Pre-Award Reports for the Grants Department. Qualifications: Bachelor's degree and/or equivalent experience. 1-3 years of NIH grants management experience. Experience with other sponsors who support biomedical research (DOD/USAMRAA, NSF, CIRM) a plus. Excellent attention to detail, outstanding customer service and impeccable communication skills are required for this position. Demonstrated pre-award management experience, including proposal development. The ability to manage a high volume of work and competing deadlines in a fast-paced, deadline-driven work environment. Comfort working remotely and using tools to facilitate remote work, e.g., Zoom, Slack. Effective analytical and creative problem solving skills. Comfort with business systems that hold financial and administrative information, such Workday. Proficiency with Microsoft Word and Excel, with particular regard to Excel formulas. Experience using electronic pre- and post-award systems such as Grants.gov Workspace, NIH ASSIST, and NSF Fastlane/Research.gov. Additional Information: Title and salary will be commensurate with education and experience. Be a part of big ideas and consider Gladstone. Your difference will make a difference in human health. Gladstone is an equal opportunity employer.

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for an Associate Director/Principal Scientist, Virology for our site in Malvern, PA. At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies. The candidate for this position will provide scientific leadership in the area of viral safety and be responsible for driving virology testing programs in raw materials, cell line characterization, unprocessed bulk testing and viral clearance studies to current industry standards and/or best practices. The candidate will provide technical review of external partners protocols, reports, methods, coordinate with and resolve issues with external laboratories and lead activities when required. Candidate may also manage direct reports. Responsibilities also include maintaining an awareness of current issues in viral safety for biopharmaceuticals, authoring technical documents, regulatory filings, supporting quality events and change controls, and contributing to technology transfer to collaboration partners. Responsible as a liaison with manufacturing sites quality control to provide technical oversight for clinical and commercial products. Knowledge of cell and gene therapy manufacturing and testing preferred. The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objectives. The position requires extensive expertise in virology, including familiarity with classical cell culture, nucleic acid testing methods and advanced viral detection systems. Requires substantial communication skills including experience with regulatory agencies, technical writing ability to ensure studies are performed properly and data presented in regulatory documents are understandable to the regulatory community. The candidate will act as a mentor, advisor, and technical subject matter expert to others in the company. Qualifications A PhD in Virology, Microbiology, Biological Sciences or Biochemistry with at least 6 years of relevant business experience OR at least 3 years of experience performing progressively advanced duties at the Senior Scientist level, or equivalent training/ experience is required with a minimum of a bachelor's degree. Knowledge and hands-on experience in cell culture, virology, and nucleic acid methods are required. Knowledge of cell therapy and gene therapy manufacturing, and testing preferred. Experience working in a GMP environment is preferred. CMC regulatory experience is preferred. Experience managing people preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects independently. Good written and verbal communication skills are required. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required. Data reporting, ability to present findings to management, and experience with team-based collaborations is a must. Occasional travel and weekend work may be required. Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Primary Location United States-Pennsylvania-Malvern-200 Great Valley Parkway Organization Janssen Research & Development, LLC (6084) Job Function R&D Requisition ID W

Principal Scientist, Cancer Biology US-MA-Cambridge Job ID: 2 Type: Regular Full-Time # of Openings: 1 Category: Research & Development Nuvalent Overview Principal Scientist, Cancer Biology With deep expertise in small molecule therapeutics, Nuvalent is creating selective medicines to address the needs of patients with cancer. Nuvalent is an exciting early-stage company and brings together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. Nuvalent is funded by Deerfield Management. Job Summary: The Principal Scientist, Cancer Biology, will contribute to the discovery and advancement of novel small molecule therapeutics for the treatment of cancer. With a deep knowledge of cancer biology, the candidate will participate in and lead cross-functional teams to provide comprehensive assessment of small molecules to support their advancement into clinical trials. The candidate will play a critical role in characterizing the biological activity of small molecules and developing new biological assays. Therefore, the ideal candidate should be proficient at a wide range of techniques in cell biology, molecular biology, biochemistry, and/or rodent studies. The candidate will also contribute to Nuvalent's product pipeline by identifying potential targets and performing literature reviews. Nuvalent collaborates heavily with external research organizations. As such, the ideal candidate has strong communication skills to represent Nuvalent and guide external studies. Nuvalent is an early-stage company that cares deeply about professional growth of its employees. The candidate will have the opportunity to work across departments with industry veterans and help build the culture for the organization. Responsibilities Opportunity and Responsibilities: Be a part of a dynamic, growing team on the leading edge of oncology drug discovery Direct in vitro testing and assay development, including biochemical and cellular assays. Direct in vivo testing and assay development. Scout new treatment opportunities and contribute to long-term scientific strategies. Interface with cross-functional teams (medicinal chemistry, computational chemistry, DMPK, and translational medicine). Qualifications Minimum Requirements Ph.D. with 7 years or BS/MS with 10 years of research experience. Degrees in disciplines of Cancer Biology, Cell Biology, Molecular Biology, Chemical Biology, and/or Biochemistry are preferred. Deep knowledge of cancer biology and cell signaling pathways. Experience working in the pharmaceutical industry. Scientific knowledge and experience, with strong analytical and problem-solving skills. Expertise in molecular biology, tissue culture and cell biology assays, including some or all of the following: real time PCR, recombinant DNA technology, western blot, immunoprecipitation, ELISA, Next Generation Sequencing, gene expression analysis, genome editing (particularly CRISPR), viral transductions, RNAi, flow cytometry, microscopy, and immunohistochemistry. Preferred: experience developing and working with in vivo cancer models. Preferred: experience with structure-activity relationship analysis, structure-guided drug design, small-molecule pharmacology, and synthetic organic chemistry. Excellent scientific and business communication skills (verbal, written and technical), strong interpersonal/collaboration skills and planning skills. Ability to think critically with strong attention to detail. Ability to work independently to determine appropriate resources to overcome challenges. Excellent team player, collaborative mindset. Nuvalent, Inc. provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. PM18 #LI-DNI PI

The Position Arcus Biosciences is seeking a Principal Statistical Scientist with broad responsibility for providing high-quality statistical expertise to assigned clinical studies and exploratory work at Arcus. He or she will look beyond the purely statistical aspects, collaborating to promote rigor in the planning, conduct, and analysis of experiments, as well as to guide the interpretation and reporting of results. The position will work directly with senior biostatisticians and will interact with a diverse group of internal and external stakeholders. The Principal Statistical Scientist initially will have statistical oversight responsibilities for clinical studies in our lung cancer and early oncology development spaces. This is a unique opportunity to join a small but growing Biometrics team investigating a diverse portfolio of (immuno-)oncology therapeutics. The ideal candidate will be motivated to integrate into clinical study teams, establish cross-functional partnerships, and have an interest in conducting exploratory data analyses involving new and diverse data types including, for example, exploratory or translational biomarker analyses in support of our clinical development plans. Job Duties and Responsibilities Serves as a biostatistician on clinical development teams and partners with other functions in the planning, design, analysis, and reporting and communication of results (internally and externally) In partnership with senior statisticians, develops fit-for-purpose clinical trial designs, with decision-making operating characteristics, power, sample size and timeline considerations, as well as other development needs addressed via their statistical toolset Ensures data and analysis quality - including working with external statistical vendors, contractors or consultants - when generating formal or informal tables, listings and figures Demonstrates a learning mindset by developing or adopting innovative, fit-for-purpose statistical methods, or tools to address scientific questions, engage in exploratory work, or support internal decision-making Builds solid collaborations with cross-functional clinical team members as well as internal and external data-facing stakeholders Keeps abreast of new developments in statistics, drug development and regulatory guidance and requirements through literature review and professional activities Qualifications Education/Experience PhD in biostatistics, statistics, mathematics or a related field. MS considered with appropriate additional experience 3+ years of biotechnology or pharmaceutical industry experience; clinical oncology experience is a strong plus Sound understanding of theoretical and applied statistics Fluency with standard statistical software (SAS or R). R programming skills a must. Strong analytical skills and demonstrated experience in gathering, analyzing, interpreting, reporting and presenting data Knowledge of industry standards for clinical data collection and data base structure, e.g., CDISC guidelines for SDTM and ADaM data sets for both CRF and non-CRF data Professional/Personal Requirements Ability to work independently on multiple projects, anticipate challenges and defend positions based on science and sound data analysis Ability to effectively communicate statistical concepts to non-statisticians Prior experience with biomarker data (especially routine companion diagnostic and/or next-gen sequencing data) and a firm understanding of biological assays is a strong plus Subject matter knowledge in the areas oncology or immunology will be a strong plus as will any specialty expertise related to one or more partner functions, e.g., clinical pharmacology, preclinical or translational research and development, bioinformatics, CMC/manufacturing, etc.

JOB PURPOSE Sana is seeking an exceptional Senior Leader to join our dynamic and growing team supporting CMC development of novel gene and cell therapy drug substances and products. The Senior Director of Process & Platform Operations is a key leadership position within Sana Technical Operations as we prepare to advance a pipeline of next-generation gene and cell therapy products to the clinic. The role will lead and build a team of production associates, engineers and scientists to provide technical leadership to establish operations for production and supply of material from research through Phase 1 GMP for novel gene therapy (viral vector) products. The team, led by this role, will establish efficient production operations to supply early research material supply, critical materials (GLP tox), and enable GMP supply by leading tech transfer to GMP manufacturing. The role has technical accountability and oversight for supply of materials from internal or external (CMO) GMP facilities, partnering with process development, analytical, and GMP manufacturing teams. The role will engage in Sana's enterprise-level manufacturing and supply chain planning, including the build out of internal GMP capabilities and external supply chain networks. In this capacity, the Leader will contribute to line-of-sight for life cycle management, with focus on process/technology improvements to the platform and assessment of product comparability. With a strong focus on both technical and operational excellence, this senior hands-on managerial position will play a leading role in shaping core production technology platforms at Sana and the advancement of therapeutic gene therapy candidates from Research into the clinic. This role represents an exciting and unique opportunity to shape the early CMC development paradigm for advanced therapies. DUTIES AND RESPONSIBILITIES The leader will oversee activities in support of early supply of quality research materials to guide pre-clinical candidate selection. With a mindset toward accelerating development, the leader will embrace both science and manufacturability to define and operationalize efficient production platforms for material supply across the early development horizon from candidate selection through to Phase 1 IND. The leader in this role will manage an operations team to supply early research, pilot scale supply and GLP study material supply, tech transfer and process establishment in GMP. The leader will participate with process and analytical development in early process characterization with an eye toward de-risking and troubleshooting production operations, use of scaledown models, and new manufacturing technology exploration. The role will be a member of the Manufacturing network leadership team and will contribute to and influence gene therapy manufacturing and network strategies, and standards for both drug substance and drug product production. The role will work closely with Process & Analytical Development, Quality, External Manufacturing, Supply Chain and CMC/product lifecycle teams to advance our pipeline and establish a robust development network for new products. The role will be viewed as a technical thought leader internally and externally in manufacturing viral vectors and complex biologics. The successful candidate will have industrial experience managing a process development team for biologics/vaccines (and/or preferably gene/cell therapy) and manufacturing operations, have a passion for delivering results and making an impact, an interest in technology and commitment to learning, and be an extraordinary collaborator in a dynamic setting. The ideal leader will shape strategy, build the capability, drive for operational excellence and continuous improvement, and manage a high-performing and growing team. Responsibilities: Establish scientifically-sound and operationally-efficient production workflows for supply of quality research-grade viral vectors for early research studies. Oversee a research production capability to support production of novel viral vector compositions for research customers, perform early optimization & manufacturability assessments, manage a lean industrial workflow to supply small-volume and high-quality vectors in line with business/customer expectations of turnaround time and capacity. Establish the requirements for the clinical manufacturing process for viral vector and ensure application of these requirements throughout the product life cycle. Leveraging a platform mindset to achieve speed and efficiency, establish processes at scale and define an approach for rapid introduction of new candidates. Be accountable for technical success of process operations in the supply of GLP and GMP material. Identify opportunities to shape both the technology platform and manufacturing operations to build a platform within Sana to increase speed, gain efficiency, increase probability of success of supply, reduce cost, and ensure quality in meeting program deliverables across the Sana portfolio of programs. As with other advanced therapies, critical attention to raw materials is a key consideration. Transfer processes developed to internal/external manufacturing sites. This includes ensuring clear definition of the clinical manufacturing control strategy and associated enabling documents/validation or supporting technical studies. Advise on developmental studies needed to ensure successful transfer and de-risking of clinical operations. Engage with Process & Analytical Development to ensure sound process qualification, control and comparability strategies are in place to support the programs. Review/author technical sections of major regulatory documents and contribute to the overall CMC strategy for vector technologies. Participate in the CMO selection process by evaluating CMO capabilities against technical requirements. Provide technical support of the CMOs for deviation management, lot disposition, batch record reviews to ensure that technical issues stay off the critical path for reliable supply. Participate in appropriate internal and joint CMO governance meetings (ex, joint steering committees). Ensure mitigation plans for significant technical risks at the CMOs or key raw material suppliers Hire and manage a team of scientists to define, operationalize, and maintain production workflows. Contribute to build-out of early product and process insights. With a focus on technical excellence, the individual will oversee production activities and their: implementation, performance, troubleshooting, and trending. With a focus on operational excellence, the individual will oversee the design, delivery, and continuous improvement of sample and analytical data workflows to address the needs of the business from the standpoint of: turnaround time, testing capacity, quality, and cost. Participate in establishment of drug substance and drug product specifications and provide technical leadership in review of content for regulatory interactions. QUALIFICATIONS Basic Qualifications Bachelors plus 12+ yrs or equivalent combination of education and work experience; expert knowledge of bioprocess principals and practice; a technical and people leader with experience managing department(s) with mid-level and senior employees. Experience with the following cell culture, purification, chromatography, clarification technologies, tangential flow and normal filtration, aseptic processing and drug product, process automation, high-throughput process development, automated liquid handling, electronic notebooks. Prior experience leading a team in Process Development, pilot scale production, tech transfer, and/or GMP manufacturing is important for success in the position. Must have exceptional organizational skills, preferably with advanced practical experience (+/-certification) in operational excellence or the management of complex workflows using Lean or Six Sigma. Solid understanding of relevant regulatory agency guidance such as FDA, ICH and EMA and hand-on experience. Ability to work in a fast-paced growth environment, and to prioritize work from multiple projects. Demonstrates a respect for others and is open to new/different ideas. Excellent written and verbal communication skills. Preferred Qualifications Bachelors plus 15 yrs or equivalent combination of education and work experience; expert knowledge of principals and concepts and is a thought leader; has experience managing department(s) with senior employees. Organizational leader with experience managing a team of direct (and indirect) reports in technical development of CMC (analytical, process, or formulation) packages for IND/CTA submission. Demonstrated track record, broad experience, and demonstrated success in process development and operations for complex biological products.

Our Bioanalytical Sciences Group is looking for a Scientist who will be Principal Investigator responsible for clinical bioanalysis of PK, Immunogenicity and biomarkers within Bioanalytical Sciences. You will serve as a key liaison between our Bioanalytical team and clinical study teams to play a meaningful role in advancing our clinical development. A Typical Day Might Look Like This: Responsible for the overall conduct of bioanalysis of pharmacokinetic, immunogenicity and biomarkers from clinical studies. Review bioanalytical data to ensure the quality and quality of data. Act as a bridge between Bioanalytical Sciences (BAS) and clinical development team, work closely with groups within BAS, the Clinical Pharmacology group, clinical study teams and other working groups to establish bioanalytical deliverables and timelines for multiple projects. Ensure they are achieved to support clinical development. Prepare and review sample analysis documentation and clinical sample analysis reports. Contributes to regulatory submissions and responses to regulatory inquiries. Review clinical study related documents including study concepts, protocols, amendments, statistical analysis plan (SAP) and clinical study reports (CSR). Review SOPs, publications, and guidelines to ensure the process for bioanalysis is in accordance with industry practice and/or regulatory expectations. Participate in internal and external project teams. Prepare and present scientific data at internal and external meetings This Job Might Be For You If: You have strong initiative and aim to complete ambitious tasks and learn new technologies. You are capable of multi-tasking, working both independently and within a team environment. Minimum two (2) years of experience in the pharmaceutical or biotech industry, experience with a Contract Research Organization (CRO) preferred.Experience with immunoassay techniques such as ELISA, ECL and MSD, as well as LC-MS/MS. Knowledge and/or experience with pharmacokinetics (PK) assays and immunogenicity assays for biotherapeutics desired. Experience with bioanalytical regulatory guidance and industry standard practice for conducting clinical bioanalysis.Familiarity with LIMS (Laboratory Information Management Systems) preferred. Writing/reviewing study reports and contributing to regulatory submissions exposure preferred. Strong project management and interpersonal skills a plus. Knowledge in Oncology a plus. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

Organization Neurona Therapeutics Position Research Associate - Discovery Biology (level of RA depends on experience) Location San Francisco Bay Area Manager Principal Scientist, Group Leader Status Exempt OVERVIEW Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological diseases. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company. Key Responsibilities: Maintain human pluripotent stem cells and differentiated cells and perform stem cell differentiation into neuronal lineages using a large variety of formats, (384 well plates, regular and large-scale culture vessels). Develop cell-based screening assays using automated liquid handler for stem cell differentiation optimization. Utilize High Content Screening (HCS) technology for high-throughput analysis of cell populations. Characterize differentiated cells (immuno cyto-chemistry, Flow cytometry, RT-QPCR, RNA sequencing). Conduct fluorescence or magnetic -activated cell sorting experiments. Prepare tissue culture reagents (media, small molecules, cytokines); Tissue culture room upkeep and restocking. Maintain detailed records. Requirements: Bachelor's degree (+2 years of relevant experience) or Master degree in cell/molecular biology or related field. Clear knowledge of sterile tissue culture technique (at least two years experience). Familiar with pluripotent stem cell culture, in vitro directed differentiation paradigms and molecular/functional characterization of derived cell types. Experience with automated liquid handlers to perform medium / high throughput cell based screenings. Experience with coding (R, Python, etc.) would be a plus. Willing to work a limited number of hours during weekends. Excellent writing, verbal communication, and interpersonal skills, proficiency with Microsoft office. Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity. Preferred Qualifications: At least one year of experience with human pluripotent (embryonic or induced) stem cell maintenance, differentiation, cell sorting and immuno cyto chemistry. One year of experience with lab automation for cell-based screening assays using liquid handling automates (protocol creation, hands on automates). Experience with transcript- and protein-based gene expression analyses, high content screening. Knowledge of human developmental biology. Neurona Therapeutics is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

Seattle Genetics Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law. #LI-CM1 Research . Bothell, Washington Summary: We are seeking a highly capable and motivated laboratory-based scientist with a technical background in cell line generation and assay development. This Research Associate will be a part of the Antibody Discovery team that generates therapeutic antibodies for our preclinical programs in oncology. The primary responsibilities will include engineering cell lines and validating their use in flow cytometry and optimizing functional assays for use in hybridoma screening. The candidate should work well within a highly collaborative team environment, while being able to work independently to design, execute, troubleshoot, optimize, and interpret experiments. Specific position level will be commensurate with applicant's experience. Principal Responsibilities: Design, execute, troubleshoot, optimize, and interpret experiments Utilize transfection, CRISPR/Cas9 tools, and lentiviral transduction for the generation of stable cell lines Design constructs for use in cell line generation, both for overexpression and knockout Evaluate target expression and validate antibody reagents by flow cytometry Design and optimize cell-based assays for lead antibody characterization, which may include ligand blocking assays or cytotoxicity assays Coordinate workflows with cross-functional teams, project leads and CROs Keep detailed and accurate laboratory records, communicate results in written and oral format, and present results at group meetings and cross-departmental meetings Maintain laboratory spaces, equipment, and supplies Qualifications: 5+ years of experience in an academic, biotech, or pharmaceutical research setting Requires 1+ years of experience in cell line generation, and must include transfection, CRISPR/Cas9 tools, and lentiviral transduction Requires hands-on experience staining cells for flow cytometry and running the instrument independently Demonstrated ability to work both independently and as part of a team in a fast-paced dynamic environment Demonstrated ability to successfully handle multiple projects simultaneously, while tracking goals and performance on team deliverables The ability to be flexible and shift individual and team priorities based on leadership and/or company changes Ability to generate high quality documentation and communicate effectively to a variety of audiences through oral and written formats Team player and solution-oriented, with strong analytical, interpersonal, organizational and time-management skills Education: Bachelor's or Master's degree in biological sciences or relevant field As the leading employer in our industry in the Pacific Northwest, Seattle Genetics is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seattle Genetics, please visit . #LI-CM1 PI