Position Overview Nektar has an exciting opportunity for a Sr. Research Associate to join their team. Seek a highly motivated Senior Research Associate with a focus in Immunology for our In vitro pharmacology research team, in our San Francisco office. The individual will participate in design and conduct of experiments in biological systems to characterize and validate novel targets, to test efficacy of potential therapeutics, and to develop relevant biomarker strategies to prioritize them for further development in a variety of disease areas, including autoimmune diseases and immuno-oncology. Knowledge of flow cytometry and mammalian cell culture is required. The candidate should also possess strong knowledge of and be proficient in relevant experimental biology techniques such as immunoassays (ELISA, MSD), qPCR, biochemical/cell-based assays, and must have experience handling primary human cells. The candidate will participate in technology development in the area of in vitro assays, cell biology, and ex vivo sample testing. The individual will be expected to document experimental findings according to approved Nektar policy, and to draft associated technical reports. The individual must maintain knowledge of state-of-the-art principles and theories, develop and analyze new product concepts by reviewing preclinical and clinical literature, and participate & contribute on discovery teams, as necessary. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Essential/Primary Duties, Functions and Responsibilities Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Normally receives general instructions on routine work, detailed instructions on new assignments. Interfaces with various departments, customers and partners. Uses professional concepts and scientific knowledge to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways. Defines problems, develops approaches and develops experiments with sound judgment and some supervision. Puts work practices in context with larger team. Writes reports and protocols. May act as a principal investigator in conducting own experiments. May participate in the development of patent applications. May provide guidance to junior scientific staff, providing training as needed, and ensures adherence to company policies and quality requirements. Requirements A minimum of a Bachelors' degree in a scientific discipline is required. A minimum of 8 years work experience in a research and/or development environment, preferably in industry, is required. Equivalent education and/or experience may be accepted. Previous supervisory experience is a plus. Must have excellent analytical skills, with significant hands on laboratory experience. Must have a demonstrated working knowledge of scientific principles. Must be able to demonstrate good decision-making skills. Must possess excellent oral and written communication skills. Must be able to work well in and promote a team environment, and demonstrate leadership abilities. Must be able to provide technical assistance to others in a wide range of laboratory based activities/techniques. Must be able to independently write reports. Must be able to demonstrate sound judgment within broadly defined practices and policies. M Must have demonstrated problem solving abilities. Strong organizational skills are required. Good computer skills, with working knowledge of MS word, Excel, PowerPoint and Graphpad Prism, are required. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
03/04/2021
Full time
Position Overview Nektar has an exciting opportunity for a Sr. Research Associate to join their team. Seek a highly motivated Senior Research Associate with a focus in Immunology for our In vitro pharmacology research team, in our San Francisco office. The individual will participate in design and conduct of experiments in biological systems to characterize and validate novel targets, to test efficacy of potential therapeutics, and to develop relevant biomarker strategies to prioritize them for further development in a variety of disease areas, including autoimmune diseases and immuno-oncology. Knowledge of flow cytometry and mammalian cell culture is required. The candidate should also possess strong knowledge of and be proficient in relevant experimental biology techniques such as immunoassays (ELISA, MSD), qPCR, biochemical/cell-based assays, and must have experience handling primary human cells. The candidate will participate in technology development in the area of in vitro assays, cell biology, and ex vivo sample testing. The individual will be expected to document experimental findings according to approved Nektar policy, and to draft associated technical reports. The individual must maintain knowledge of state-of-the-art principles and theories, develop and analyze new product concepts by reviewing preclinical and clinical literature, and participate & contribute on discovery teams, as necessary. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Essential/Primary Duties, Functions and Responsibilities Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Normally receives general instructions on routine work, detailed instructions on new assignments. Interfaces with various departments, customers and partners. Uses professional concepts and scientific knowledge to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways. Defines problems, develops approaches and develops experiments with sound judgment and some supervision. Puts work practices in context with larger team. Writes reports and protocols. May act as a principal investigator in conducting own experiments. May participate in the development of patent applications. May provide guidance to junior scientific staff, providing training as needed, and ensures adherence to company policies and quality requirements. Requirements A minimum of a Bachelors' degree in a scientific discipline is required. A minimum of 8 years work experience in a research and/or development environment, preferably in industry, is required. Equivalent education and/or experience may be accepted. Previous supervisory experience is a plus. Must have excellent analytical skills, with significant hands on laboratory experience. Must have a demonstrated working knowledge of scientific principles. Must be able to demonstrate good decision-making skills. Must possess excellent oral and written communication skills. Must be able to work well in and promote a team environment, and demonstrate leadership abilities. Must be able to provide technical assistance to others in a wide range of laboratory based activities/techniques. Must be able to independently write reports. Must be able to demonstrate sound judgment within broadly defined practices and policies. M Must have demonstrated problem solving abilities. Strong organizational skills are required. Good computer skills, with working knowledge of MS word, Excel, PowerPoint and Graphpad Prism, are required. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar has an exciting opportunity for a Sr. Director, Drug Safety to join their team. Overall responsibility for leading the Drug Safety Team and directing the safety surveillance of all company investigational drug products in development and for managing patient safety and meeting regulatory reporting requirements.. Actively participates in the oversight of patient safety in all on-going clinical trials. Directs and conducts ongoing safety surveillance of company drug products. Analyses changing risk/benefit profile of company drugs in clinical trials to identify potential safety signals and implements appropriate safety updates and risk mitigation plans. Manages compliance with SOPs and FDA and global regulations for the reporting of adverse events to regulatory authorities. Serves as medical safety expert for all products in various stages of development. Lead role to help respond to and resolve safety questions from regulatory authorities, as well as regulatory agency audits and corrective action plans. Manages internal staff and external resources to ensure delivery of quality pharmacovigilance servicses. Directs the development and preparation of reports for company management, as well as for external regulatory agencies. Directs the development and preparation of periodic and annual safety reports , investigator communications,product labeling/package inserts and other reports as necessary. Provides strategic planning, implementation, and management of drug safey operations to support clinical development of company products. Provides medical expert safety review input into all critical documents for clinical development of products. Helps select, develop,train, and evaluate personnel to ensure the efficient operation of the drug safety function. This job contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Consistently works on abstract problems across functional areas of clinical development and medical affairs. Identifies and evaluates fundamental issues, providing strategy and direction for major functional areas involved with clinical development of pharmaceutical/biotech products. Interacts internally and externally with executive level management requiring negotiation of extremely difficult matters to influence policymaking bodies. Leads and directs the Drug Safety Team and all aspects of drug safety related to all company sponsored clinical development activities to manage patient safety and compliance with regulatory reporting requirements. Actively participates in oversight of patient safety in all on-going clinical trials. Directs and conducts ongoing safety surveillance of company drug products. Manages internal staff and external resources to ensure delivery of quality pharmacovigilance services. Negotiates contracts, interacts and supervises the activities of contract organizations and consultants for pharmacovigilance services. Provides ongoing advice to senior management on the changing risk-benefit profile of company drug products in clinical trials, based on analyses/evaluation of potential safety signals and implements appropriate safety updates and risk mitigation plans. Provides oversight of all clinical safety services including review of medical coding of adverse event data and management of SAEs through the entire lifecycle including preparation of similar-event analyses for unexpected and related serious adverse events (SAEs) from clinical trials. Manages compliance with SOPs, and FDA and global regulations for the reporting of adverse events to regulatory agencies, IRB/Ethics committees and Investigators. Serves as the medical safety expert for all products at all stages of clinical development (Phase 1, 2 and 3 and post-approval). Plays lead role to help respond to and resolve safety questions from regulatory authorities, as well as regulatory agency audits and corrective action plans. Supports drug safety function and effectively interfaces with all relevant cross functional departments and personnel to ensure safety training and compliance, and readiness level to pass internal/external audits. Directs the development and preparation of reports for company management, as well as for external regulatory agencies. Directs the development, preparation and compliance of periodic and annual safety reports (eg. US IND annual progress reports, EU annual safety reports, periodic line listings, NDA safety updates, etc.), investigator communications, product labeling/package inserts and other reports as necessary. Provides strategic planning, implementation, and management of drug safey operations to support clinical development of company products. Participates with other senior managers to establish strategic plans for the clinical development plan of investigational products. Provides medical expert safety review input into all critical documents for clinical development of products (eg. protocols and amendments, ICFs, IBs, IMPDs, clinical research reports, , INDs, CTAs, etc). Establishes and manages independent Data Safety Monitoring Boards (DSMBs) for clinical studies, if required. Performs research on safety profiles of competitor products within therapeutic areas of interest to help develop effective competitive strategies, for clinical development of company drug products. Helps recruit and select personnel, and provides training, development, coaching and regular performance review feedback to direct reports. Participates in corporate development of methods, techniques and evaluation criteria for projects, programs, and people. Ensures departmental budgets and schedules meet corporate requirements. An MD degree is required. A minimum of 9 years of relevant drug safety experience is required. A minimum of 7 years previous management experience may be required. An in-depth knowledge and thorough understanding of FDA, EU, and global regulations, ICH guidelines, and GCPs that govern drug safety and pharmacovigilance are required. Experience with safety databases, and expertise in clinical safety assessments, safety signal detection and risk management, including interactions with regulatory authorities are required. Must be able to demonstrate extensive experience in the design of clinical studies and have a strong working knowledge of safety reviews for input into critical documents for drug development. Strong oral and written communication skills are required. Must have a demonstrated ability to solve problems with innovative solutions along with strong organizational skills. Excellent written and verbal communication skills are required. Previous experience working with senior management is required. Experience in conducting formal presentations to Sr. Management and key opinion leaders is required. Ability to research and understand the safety profiles of competitor products within therapeutic areas of interest to help develop effective competitive strategies, as well as an in-depth understanding of clinical product development in the pharmaceutical industry. Strong analytical skills, especially with regard to understanding and interpreting scientific research and literature are essential. Knowledge of GMP and GLP is preferred. Must be a demonstrated self-starter and team player with strong interpersonal skills. Must have strong computer skills with a proficiency in various software applications (eg. Microsoft Project, Word, Excel, Visio, PowerPoint). We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/28/2021
Full time
Position Overview Nektar has an exciting opportunity for a Sr. Director, Drug Safety to join their team. Overall responsibility for leading the Drug Safety Team and directing the safety surveillance of all company investigational drug products in development and for managing patient safety and meeting regulatory reporting requirements.. Actively participates in the oversight of patient safety in all on-going clinical trials. Directs and conducts ongoing safety surveillance of company drug products. Analyses changing risk/benefit profile of company drugs in clinical trials to identify potential safety signals and implements appropriate safety updates and risk mitigation plans. Manages compliance with SOPs and FDA and global regulations for the reporting of adverse events to regulatory authorities. Serves as medical safety expert for all products in various stages of development. Lead role to help respond to and resolve safety questions from regulatory authorities, as well as regulatory agency audits and corrective action plans. Manages internal staff and external resources to ensure delivery of quality pharmacovigilance servicses. Directs the development and preparation of reports for company management, as well as for external regulatory agencies. Directs the development and preparation of periodic and annual safety reports , investigator communications,product labeling/package inserts and other reports as necessary. Provides strategic planning, implementation, and management of drug safey operations to support clinical development of company products. Provides medical expert safety review input into all critical documents for clinical development of products. Helps select, develop,train, and evaluate personnel to ensure the efficient operation of the drug safety function. This job contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Consistently works on abstract problems across functional areas of clinical development and medical affairs. Identifies and evaluates fundamental issues, providing strategy and direction for major functional areas involved with clinical development of pharmaceutical/biotech products. Interacts internally and externally with executive level management requiring negotiation of extremely difficult matters to influence policymaking bodies. Leads and directs the Drug Safety Team and all aspects of drug safety related to all company sponsored clinical development activities to manage patient safety and compliance with regulatory reporting requirements. Actively participates in oversight of patient safety in all on-going clinical trials. Directs and conducts ongoing safety surveillance of company drug products. Manages internal staff and external resources to ensure delivery of quality pharmacovigilance services. Negotiates contracts, interacts and supervises the activities of contract organizations and consultants for pharmacovigilance services. Provides ongoing advice to senior management on the changing risk-benefit profile of company drug products in clinical trials, based on analyses/evaluation of potential safety signals and implements appropriate safety updates and risk mitigation plans. Provides oversight of all clinical safety services including review of medical coding of adverse event data and management of SAEs through the entire lifecycle including preparation of similar-event analyses for unexpected and related serious adverse events (SAEs) from clinical trials. Manages compliance with SOPs, and FDA and global regulations for the reporting of adverse events to regulatory agencies, IRB/Ethics committees and Investigators. Serves as the medical safety expert for all products at all stages of clinical development (Phase 1, 2 and 3 and post-approval). Plays lead role to help respond to and resolve safety questions from regulatory authorities, as well as regulatory agency audits and corrective action plans. Supports drug safety function and effectively interfaces with all relevant cross functional departments and personnel to ensure safety training and compliance, and readiness level to pass internal/external audits. Directs the development and preparation of reports for company management, as well as for external regulatory agencies. Directs the development, preparation and compliance of periodic and annual safety reports (eg. US IND annual progress reports, EU annual safety reports, periodic line listings, NDA safety updates, etc.), investigator communications, product labeling/package inserts and other reports as necessary. Provides strategic planning, implementation, and management of drug safey operations to support clinical development of company products. Participates with other senior managers to establish strategic plans for the clinical development plan of investigational products. Provides medical expert safety review input into all critical documents for clinical development of products (eg. protocols and amendments, ICFs, IBs, IMPDs, clinical research reports, , INDs, CTAs, etc). Establishes and manages independent Data Safety Monitoring Boards (DSMBs) for clinical studies, if required. Performs research on safety profiles of competitor products within therapeutic areas of interest to help develop effective competitive strategies, for clinical development of company drug products. Helps recruit and select personnel, and provides training, development, coaching and regular performance review feedback to direct reports. Participates in corporate development of methods, techniques and evaluation criteria for projects, programs, and people. Ensures departmental budgets and schedules meet corporate requirements. An MD degree is required. A minimum of 9 years of relevant drug safety experience is required. A minimum of 7 years previous management experience may be required. An in-depth knowledge and thorough understanding of FDA, EU, and global regulations, ICH guidelines, and GCPs that govern drug safety and pharmacovigilance are required. Experience with safety databases, and expertise in clinical safety assessments, safety signal detection and risk management, including interactions with regulatory authorities are required. Must be able to demonstrate extensive experience in the design of clinical studies and have a strong working knowledge of safety reviews for input into critical documents for drug development. Strong oral and written communication skills are required. Must have a demonstrated ability to solve problems with innovative solutions along with strong organizational skills. Excellent written and verbal communication skills are required. Previous experience working with senior management is required. Experience in conducting formal presentations to Sr. Management and key opinion leaders is required. Ability to research and understand the safety profiles of competitor products within therapeutic areas of interest to help develop effective competitive strategies, as well as an in-depth understanding of clinical product development in the pharmaceutical industry. Strong analytical skills, especially with regard to understanding and interpreting scientific research and literature are essential. Knowledge of GMP and GLP is preferred. Must be a demonstrated self-starter and team player with strong interpersonal skills. Must have strong computer skills with a proficiency in various software applications (eg. Microsoft Project, Word, Excel, Visio, PowerPoint). We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar has an exciting opportunity for a Sr. Research Associate to join their team. Seek a highly motivated Senior Research Associate with a focus in Immunology for our In vitro pharmacology research team, in our San Francisco office. The individual will participate in design and conduct of experiments in biological systems to characterize and validate novel targets, to test efficacy of potential therapeutics, and to develop relevant biomarker strategies to prioritize them for further development in a variety of disease areas, including autoimmune diseases and immuno-oncology. Knowledge of flow cytometry and mammalian cell culture is required. The candidate should also possess strong knowledge of and be proficient in relevant experimental biology techniques such as immunoassays (ELISA, MSD), qPCR, biochemical/cell-based assays, and must have experience handling primary human cells. The candidate will participate in technology development in the area of in vitro assays, cell biology, and ex vivo sample testing. The individual will be expected to document experimental findings according to approved Nektar policy, and to draft associated technical reports. The individual must maintain knowledge of state-of-the-art principles and theories, develop and analyze new product concepts by reviewing preclinical and clinical literature, and participate & contribute on discovery teams, as necessary. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Essential/Primary Duties, Functions and Responsibilities Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Normally receives general instructions on routine work, detailed instructions on new assignments. Interfaces with various departments, customers and partners. Uses professional concepts and scientific knowledge to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways. Defines problems, develops approaches and develops experiments with sound judgment and some supervision. Puts work practices in context with larger team. Writes reports and protocols. May act as a principal investigator in conducting own experiments. May participate in the development of patent applications. May provide guidance to junior scientific staff, providing training as needed, and ensures adherence to company policies and quality requirements. Requirements A minimum of a Bachelors' degree in a scientific discipline is required. A minimum of 8 years work experience in a research and/or development environment, preferably in industry, is required. Equivalent education and/or experience may be accepted. Previous supervisory experience is a plus. Must have excellent analytical skills, with significant hands on laboratory experience. Must have a demonstrated working knowledge of scientific principles. Must be able to demonstrate good decision-making skills. Must possess excellent oral and written communication skills. Must be able to work well in and promote a team environment, and demonstrate leadership abilities. Must be able to provide technical assistance to others in a wide range of laboratory based activities/techniques. Must be able to independently write reports. Must be able to demonstrate sound judgment within broadly defined practices and policies. M Must have demonstrated problem solving abilities. Strong organizational skills are required. Good computer skills, with working knowledge of MS word, Excel, PowerPoint and Graphpad Prism, are required. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/26/2021
Full time
Position Overview Nektar has an exciting opportunity for a Sr. Research Associate to join their team. Seek a highly motivated Senior Research Associate with a focus in Immunology for our In vitro pharmacology research team, in our San Francisco office. The individual will participate in design and conduct of experiments in biological systems to characterize and validate novel targets, to test efficacy of potential therapeutics, and to develop relevant biomarker strategies to prioritize them for further development in a variety of disease areas, including autoimmune diseases and immuno-oncology. Knowledge of flow cytometry and mammalian cell culture is required. The candidate should also possess strong knowledge of and be proficient in relevant experimental biology techniques such as immunoassays (ELISA, MSD), qPCR, biochemical/cell-based assays, and must have experience handling primary human cells. The candidate will participate in technology development in the area of in vitro assays, cell biology, and ex vivo sample testing. The individual will be expected to document experimental findings according to approved Nektar policy, and to draft associated technical reports. The individual must maintain knowledge of state-of-the-art principles and theories, develop and analyze new product concepts by reviewing preclinical and clinical literature, and participate & contribute on discovery teams, as necessary. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Essential/Primary Duties, Functions and Responsibilities Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Normally receives general instructions on routine work, detailed instructions on new assignments. Interfaces with various departments, customers and partners. Uses professional concepts and scientific knowledge to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways. Defines problems, develops approaches and develops experiments with sound judgment and some supervision. Puts work practices in context with larger team. Writes reports and protocols. May act as a principal investigator in conducting own experiments. May participate in the development of patent applications. May provide guidance to junior scientific staff, providing training as needed, and ensures adherence to company policies and quality requirements. Requirements A minimum of a Bachelors' degree in a scientific discipline is required. A minimum of 8 years work experience in a research and/or development environment, preferably in industry, is required. Equivalent education and/or experience may be accepted. Previous supervisory experience is a plus. Must have excellent analytical skills, with significant hands on laboratory experience. Must have a demonstrated working knowledge of scientific principles. Must be able to demonstrate good decision-making skills. Must possess excellent oral and written communication skills. Must be able to work well in and promote a team environment, and demonstrate leadership abilities. Must be able to provide technical assistance to others in a wide range of laboratory based activities/techniques. Must be able to independently write reports. Must be able to demonstrate sound judgment within broadly defined practices and policies. M Must have demonstrated problem solving abilities. Strong organizational skills are required. Good computer skills, with working knowledge of MS word, Excel, PowerPoint and Graphpad Prism, are required. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar has an exciting opportunity for a Research Associate III to join their Non-Clinical PK Team. The Non-Clinical PK department within Nektar Therapeutics is seeking to hire a highly motivated and experienced Research Associate III. Will be responsible for large molecule bioanalysis including biomarkers in support of our immuno-oncology and immunology programs. The successful candidate will develop immunoassay/ligand binding assays (LBAs) and other bioassays or cell-based assays for the quantification of large molecule drug candidates, biomarkers, and anti-drug antibodies in biological matrices to support preclinical PK/PD/TK studies. S/he will apply the technical expertise in the design, execution and interpretation of experiments that contribute to project strategies. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs Develop robust immunoassays/ligand binding assays and other bioassays or cell-based assays for the quantification of large molecule drug candidates, biomarkers, and anti-drug antibodies in biological matrices Conduct bioanalytical sample analysis for non-GLP PK/PD/TK studies Analyze, interpret, summarize and present large molecule DMPK/BA data to internal project teams Write, edit, and finalize DMPK/BA technical reports supporting regulatory filings Stay current with the latest bioanalytical methods and technologies; identify, evaluate and implement the new technologies as needed Serve as a liaison between Non-clinical PK and the translational group as well the regulated BA group for method transfer Maintains accurate and well-organized laboratory records, worksheets, and notebooks Compliant to company Environmental Health and Safety policies, procedures, and practices A minimum of a Bachelor's degree in a scientific discipline (biochemistry / cell biology / immunology) is required. Equivalent experience may be accepted. A minimum of 5 years work experience in a research and/or development environment is required. Must have hands-on experience in immunoassay/ligand binding assay development, execution and troubleshooting, and conduct of large molecule bioanalysis and quantification in biological matrices. Strong background on immunoassay technologies, such as ELISA (direct and indirect sandwitch formats), Luminescence, Colorimetric, Electrochemiluminescence (MSD), etc to support preclinical PK/PD/TK studies. Knowledge and experience with mass spectrometric analysis and quantification of proteins is a plus. Experience with developing automated sample handling and assay processes is desirable. Knowledge of GLP, GCP, Bioanalytical and immunogenicity guidance (FDA/EMA) is a plus. A working knowledge of large molecule pharmacokinetics and protein biochemistry and characterization would be beneficial. Must possess good oral, presentation, and written communication skills. Good computer skills are required. Working knowledge of MS word, Excel and Power point. Must be willing to work as part of a team. Must be able to demonstrate good interpersonal skills. Other traits: Self-motivated, fast paced environment, able to find alternative solutions. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/22/2021
Full time
Position Overview Nektar has an exciting opportunity for a Research Associate III to join their Non-Clinical PK Team. The Non-Clinical PK department within Nektar Therapeutics is seeking to hire a highly motivated and experienced Research Associate III. Will be responsible for large molecule bioanalysis including biomarkers in support of our immuno-oncology and immunology programs. The successful candidate will develop immunoassay/ligand binding assays (LBAs) and other bioassays or cell-based assays for the quantification of large molecule drug candidates, biomarkers, and anti-drug antibodies in biological matrices to support preclinical PK/PD/TK studies. S/he will apply the technical expertise in the design, execution and interpretation of experiments that contribute to project strategies. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs Develop robust immunoassays/ligand binding assays and other bioassays or cell-based assays for the quantification of large molecule drug candidates, biomarkers, and anti-drug antibodies in biological matrices Conduct bioanalytical sample analysis for non-GLP PK/PD/TK studies Analyze, interpret, summarize and present large molecule DMPK/BA data to internal project teams Write, edit, and finalize DMPK/BA technical reports supporting regulatory filings Stay current with the latest bioanalytical methods and technologies; identify, evaluate and implement the new technologies as needed Serve as a liaison between Non-clinical PK and the translational group as well the regulated BA group for method transfer Maintains accurate and well-organized laboratory records, worksheets, and notebooks Compliant to company Environmental Health and Safety policies, procedures, and practices A minimum of a Bachelor's degree in a scientific discipline (biochemistry / cell biology / immunology) is required. Equivalent experience may be accepted. A minimum of 5 years work experience in a research and/or development environment is required. Must have hands-on experience in immunoassay/ligand binding assay development, execution and troubleshooting, and conduct of large molecule bioanalysis and quantification in biological matrices. Strong background on immunoassay technologies, such as ELISA (direct and indirect sandwitch formats), Luminescence, Colorimetric, Electrochemiluminescence (MSD), etc to support preclinical PK/PD/TK studies. Knowledge and experience with mass spectrometric analysis and quantification of proteins is a plus. Experience with developing automated sample handling and assay processes is desirable. Knowledge of GLP, GCP, Bioanalytical and immunogenicity guidance (FDA/EMA) is a plus. A working knowledge of large molecule pharmacokinetics and protein biochemistry and characterization would be beneficial. Must possess good oral, presentation, and written communication skills. Good computer skills are required. Working knowledge of MS word, Excel and Power point. Must be willing to work as part of a team. Must be able to demonstrate good interpersonal skills. Other traits: Self-motivated, fast paced environment, able to find alternative solutions. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar has an exciting opportunity for a Manager, Accounting to join their Finance team. Manages the activities of general accounting functions. Develops, implements, and maintains systems, procedures and policies, including all general accounting functions. Ensures the accurate compilation, analysis and reporting of accounting data. Acts as a liaison between the company, government, CPA and other auditors in providing the required information and ensuring that proper information is maintained for historical purposes. Supports the preparation of federal, state and local reports and tax returns. Creates and interprets reports and records for management. Supports management in the preparation of management reporting, financial analysis and financial statements. May select, develop, and evaluate personnel to ensure the efficient operation of the function. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals. Recommends changes to policies and establishes procedures that affect immediate organization(s). Works on issues of diverse scope where analysis of situation or data requires evaluation of a variety of factors, including an understanding of current business trends. Follows processes and operational policies in selecting methods and techniques for obtaining solutions. Develops and administers schedules, performance requirements and metrics. May have budget responsibilities. Supports the monthly consolidation and closing of the financial reporting records by assuming responsibility to independently complete specific and significant activities. Ensures the accuracy of financial and management reporting by independently completing trend analyses and reconciliation of balance sheet balances with transaction ledgers. Maintains the organization of accounts, departments and projects within the accounting systems to support all requested reporting. Reviews the accuracy of financial reports by analyzing variances between actuals and plan for significant and unusual activity. Assesses areas in which additional accruals may be necessary to cover the Company's business activities. Develops and maintains reports to support financial reporting, management requests and needs for analysis. Interfaces with the external auditors to explain the Company's financial reporting and accounting policies while satisfying the auditors' requests for analysis. Manages and coordinates the preparation and compilation of financial schedules for annual income tax and other tax returns. Maintains working knowledge of new GAAP pronouncements to recommend changes to procedures and reporting in order to achieve compliance. Supports any computer system enhancements and implementations that might impact the financial and management reporting. Responsible for monitoring internal controls to ensure the accuracy of financial reporting and recommends corrective actions. Performs other special projects related to analysis and activities requested by management. May provide regular performance feedback, development and coaching to junior accounting staff. A minimum of a Bachelors degree in a Finance or Business discipline is required. A CPA, MBA or other advanced degree is preferred. Equivalent experience may be accepted. A minimum of 8 years previous accounting experience, preferably in the biotech or pharmaceutical industry is required. Previous corporate accounting experience is required. A minimum of 4 years experience in public accounting is highly preferred. A minimum of 3 years experience at a publicly traded company is highly preferred. May require a minimum of 5 years previous management experience. Must be able to demonstrate a thorough knowledge of GAAP. Must be able to demonstrate a high attention to detail with an ability to independently prioritize and organize work assignments. Must possess excellent computer and analytical skills with proficiency in Excel and Word. Good communication skills both oral and written are required. Previous experience with JDE ERP and Business Objects reporting software are highly desired. Must be able to review and understand significant agreements as they pertain to the accounting group. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/21/2021
Full time
Position Overview Nektar has an exciting opportunity for a Manager, Accounting to join their Finance team. Manages the activities of general accounting functions. Develops, implements, and maintains systems, procedures and policies, including all general accounting functions. Ensures the accurate compilation, analysis and reporting of accounting data. Acts as a liaison between the company, government, CPA and other auditors in providing the required information and ensuring that proper information is maintained for historical purposes. Supports the preparation of federal, state and local reports and tax returns. Creates and interprets reports and records for management. Supports management in the preparation of management reporting, financial analysis and financial statements. May select, develop, and evaluate personnel to ensure the efficient operation of the function. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs. Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals. Recommends changes to policies and establishes procedures that affect immediate organization(s). Works on issues of diverse scope where analysis of situation or data requires evaluation of a variety of factors, including an understanding of current business trends. Follows processes and operational policies in selecting methods and techniques for obtaining solutions. Develops and administers schedules, performance requirements and metrics. May have budget responsibilities. Supports the monthly consolidation and closing of the financial reporting records by assuming responsibility to independently complete specific and significant activities. Ensures the accuracy of financial and management reporting by independently completing trend analyses and reconciliation of balance sheet balances with transaction ledgers. Maintains the organization of accounts, departments and projects within the accounting systems to support all requested reporting. Reviews the accuracy of financial reports by analyzing variances between actuals and plan for significant and unusual activity. Assesses areas in which additional accruals may be necessary to cover the Company's business activities. Develops and maintains reports to support financial reporting, management requests and needs for analysis. Interfaces with the external auditors to explain the Company's financial reporting and accounting policies while satisfying the auditors' requests for analysis. Manages and coordinates the preparation and compilation of financial schedules for annual income tax and other tax returns. Maintains working knowledge of new GAAP pronouncements to recommend changes to procedures and reporting in order to achieve compliance. Supports any computer system enhancements and implementations that might impact the financial and management reporting. Responsible for monitoring internal controls to ensure the accuracy of financial reporting and recommends corrective actions. Performs other special projects related to analysis and activities requested by management. May provide regular performance feedback, development and coaching to junior accounting staff. A minimum of a Bachelors degree in a Finance or Business discipline is required. A CPA, MBA or other advanced degree is preferred. Equivalent experience may be accepted. A minimum of 8 years previous accounting experience, preferably in the biotech or pharmaceutical industry is required. Previous corporate accounting experience is required. A minimum of 4 years experience in public accounting is highly preferred. A minimum of 3 years experience at a publicly traded company is highly preferred. May require a minimum of 5 years previous management experience. Must be able to demonstrate a thorough knowledge of GAAP. Must be able to demonstrate a high attention to detail with an ability to independently prioritize and organize work assignments. Must possess excellent computer and analytical skills with proficiency in Excel and Word. Good communication skills both oral and written are required. Previous experience with JDE ERP and Business Objects reporting software are highly desired. Must be able to review and understand significant agreements as they pertain to the accounting group. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar is seeking a talented, experienced, and highly motivated scientific expert to join our Analytical Development department in support of the company's growing pipeline of therapeutic biologics drugs. Nektar is seeking a talented, experienced, and highly motivated scientific expert to join our Analytical Development department in support of the company's growing pipeline of therapeutic biologics drugs. The successful candidate will have important leadership roles in the company's growth, with respect to the development of both products and the organization, through expertise in product characterization, analytical method development/validation and IND/BLA document preparation. The position, which will be located at the company's San Francisco, CA headquarters, will also have a significant amount of direct interactions with staff at our Huntsville, AL site, and also with our contract laboratories and contract manufacturing facilities. The individual in this position will serve as a collaborator and a scientific and technical leader on a variety of teams within the company and will represent the company in the same roles during interactions with regulatory agencies, corporate partners and collaborators. Essential Duties and Responsibilities Scientific oversight of analytical development for recombinant DNA-derived biologics products (process intermediates, protein intermediate, PEGylated drug substance and drug product), including activities performed internally and at contract facilities: Product characterization Analytical method development, optimization, transfer, and qualification/validation Quality control testing, especially cGMP Will create and own the strategic plans regarding the development and implementation of methods, techniques, and evaluation criteria. Maintains a current knowledge of state-of-the-art technological, scientific and regulatory trends. Provides scientific/technical guidance, leadership and decision-making across the company, including non-analytical functions, as appropriate. Works on issues where analysis of situations or data requires an in-depth knowledge of organizational objectives as well as an understanding of the business. Assesses utilization of resources and identifies when, and where additional resources may be needed. Communicates cross-functionally with various departments to ensure appropriate project support. Reviews and approves analytical laboratory documentation, including (but not limited to) technical reports, method transfer/qualification/validation protocols and reports, investigation protocols and reports, stability protocols, certificates of testing/analysis. Serves as the lead author of product specifications as necessary. Collaborates with quality control and stability functions (internal and external) as required to support project teams and functional areas across the company and with external partners. Participates on project teams, product development teams, company initiative task forces, and collaborations with corporate partners as the analytical development SME. Participates in the development of RFP's, review of proposals, and selection of contract facilities, including analytical and manufacturing, as the analytical SME. Reviews and approves manufacturing batch records with respect to sampling plans and analytical testing. Participates in the development of budgets associated with projects, capital equipment and staffing (internal and outsourced). Authors regulatory filing sections associated with analytical characterization and quality control. Establishes goals, structures experiments, analyzes and reduces data, recommends and plans actions to achieve project objectives. Establishes and assures adherence to schedules, work plans and performance requirements. Regularly interacts with senior management. Minimum Qualification Requirements A minimum of a Bachelor's degree in a life sciences, chemistry, or engineering discipline is required; an advanced degree is strongly preferred. A minimum of 13 years of experience in the biotechnology and/or pharmaceutical industry is required. A minimum of 10 years of experience in the analytical development of therapeutic proteins or other biologics, with a proven track record of managing and advancing both groups and projects, is required. Expertise in biopharmaceutical cGMP is essential. In-depth familiarity with state-of-the-art analytical techniques to elucidate protein structure and function is required. Experience in developing recombinant DNA-derived therapeutics from both microbial and mammalian sources is highly desired, as is experience in the development of biologics modified with PEG or other molecular entities. A track record in collaboration with representatives across multiple technical functions, including (but not limited to) Process Development, Formulation/Drug Product Development, Manufacturing, Quality Assurance, and Regulatory Affairs, is required. Prior experience with technology transfer and providing oversight to contract manufacturing organizations and contract testing laboratories is essential. Prior experience with authorship in regulatory filings and regulatory agency interactions is required; experience with BLA/NDA/MAA filings is advantageous. Experience in setting business-appropriate expectations for staff and project teams is required. A proven ability to develop and manage to a budget is a must. Excellent verbal and written communication and teamwork skills are required. Strong project management skills are essential, especially the ability to negotiate proper milestones and track progress against them. Demonstrated ability to develop successful relationships with and influence stakeholders, both internal and external, is essential. The ability to change the thinking or to gain acceptance of others in sensitive situations, using strong negotiation and influencing skills, is essential. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/16/2021
Full time
Position Overview Nektar is seeking a talented, experienced, and highly motivated scientific expert to join our Analytical Development department in support of the company's growing pipeline of therapeutic biologics drugs. Nektar is seeking a talented, experienced, and highly motivated scientific expert to join our Analytical Development department in support of the company's growing pipeline of therapeutic biologics drugs. The successful candidate will have important leadership roles in the company's growth, with respect to the development of both products and the organization, through expertise in product characterization, analytical method development/validation and IND/BLA document preparation. The position, which will be located at the company's San Francisco, CA headquarters, will also have a significant amount of direct interactions with staff at our Huntsville, AL site, and also with our contract laboratories and contract manufacturing facilities. The individual in this position will serve as a collaborator and a scientific and technical leader on a variety of teams within the company and will represent the company in the same roles during interactions with regulatory agencies, corporate partners and collaborators. Essential Duties and Responsibilities Scientific oversight of analytical development for recombinant DNA-derived biologics products (process intermediates, protein intermediate, PEGylated drug substance and drug product), including activities performed internally and at contract facilities: Product characterization Analytical method development, optimization, transfer, and qualification/validation Quality control testing, especially cGMP Will create and own the strategic plans regarding the development and implementation of methods, techniques, and evaluation criteria. Maintains a current knowledge of state-of-the-art technological, scientific and regulatory trends. Provides scientific/technical guidance, leadership and decision-making across the company, including non-analytical functions, as appropriate. Works on issues where analysis of situations or data requires an in-depth knowledge of organizational objectives as well as an understanding of the business. Assesses utilization of resources and identifies when, and where additional resources may be needed. Communicates cross-functionally with various departments to ensure appropriate project support. Reviews and approves analytical laboratory documentation, including (but not limited to) technical reports, method transfer/qualification/validation protocols and reports, investigation protocols and reports, stability protocols, certificates of testing/analysis. Serves as the lead author of product specifications as necessary. Collaborates with quality control and stability functions (internal and external) as required to support project teams and functional areas across the company and with external partners. Participates on project teams, product development teams, company initiative task forces, and collaborations with corporate partners as the analytical development SME. Participates in the development of RFP's, review of proposals, and selection of contract facilities, including analytical and manufacturing, as the analytical SME. Reviews and approves manufacturing batch records with respect to sampling plans and analytical testing. Participates in the development of budgets associated with projects, capital equipment and staffing (internal and outsourced). Authors regulatory filing sections associated with analytical characterization and quality control. Establishes goals, structures experiments, analyzes and reduces data, recommends and plans actions to achieve project objectives. Establishes and assures adherence to schedules, work plans and performance requirements. Regularly interacts with senior management. Minimum Qualification Requirements A minimum of a Bachelor's degree in a life sciences, chemistry, or engineering discipline is required; an advanced degree is strongly preferred. A minimum of 13 years of experience in the biotechnology and/or pharmaceutical industry is required. A minimum of 10 years of experience in the analytical development of therapeutic proteins or other biologics, with a proven track record of managing and advancing both groups and projects, is required. Expertise in biopharmaceutical cGMP is essential. In-depth familiarity with state-of-the-art analytical techniques to elucidate protein structure and function is required. Experience in developing recombinant DNA-derived therapeutics from both microbial and mammalian sources is highly desired, as is experience in the development of biologics modified with PEG or other molecular entities. A track record in collaboration with representatives across multiple technical functions, including (but not limited to) Process Development, Formulation/Drug Product Development, Manufacturing, Quality Assurance, and Regulatory Affairs, is required. Prior experience with technology transfer and providing oversight to contract manufacturing organizations and contract testing laboratories is essential. Prior experience with authorship in regulatory filings and regulatory agency interactions is required; experience with BLA/NDA/MAA filings is advantageous. Experience in setting business-appropriate expectations for staff and project teams is required. A proven ability to develop and manage to a budget is a must. Excellent verbal and written communication and teamwork skills are required. Strong project management skills are essential, especially the ability to negotiate proper milestones and track progress against them. Demonstrated ability to develop successful relationships with and influence stakeholders, both internal and external, is essential. The ability to change the thinking or to gain acceptance of others in sensitive situations, using strong negotiation and influencing skills, is essential. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Position Overview Nektar has an exciting opportunity for a Manager, Financial Planning & Analysis to join their Finance & Accounting team. Track and complete compilation of annual budget and long-term financial plans. Key contributor to the annual consolidated budget process. Monitors status compared to budgets and forecasts for the company in total, by program and/or by function. Prepares financial analyses of recurring and non-recurring transactions to enable Finance review. May supervise & direct the activities of the financial planning & analysis staff. Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals. Recommends changes to policies and establishes procedures that affect the immediate organization. Works on issues of diverse scope where analysis of situation or data requires evaluation of a variety of factors, including an understanding of current business trends. Follows processes and operational policies in selecting methods and techniques for obtaining solutions. Develops and administers schedules and performance requirements, may have budget responsibilities. Develop and continually refine corporate performance metrics to aid management in achieving objectives. Ensure clear and effective communication between cross functional groups on matters relating to budgeting, planning, metrics, etc. Responsible for the management of a functional area in the Finance organization. May provide guidance to junior staff within the latitude of established company policies. Acts as advisor to junior staff to meet schedules and/or resolve technical problems. May be responsible for providing regular performance feedback, development and coaching to direct reports. Additionally, the duties and responsibilities of this role entails: Budgeting, forecasting & financial analyses: Oversees and performs the financial requirements for corporate, including: Prepares financial analyses to enable Finance review and evaluation of annual budgets and proposed transactions by Executive Director, Chief Accounting Officer and Chief Financial Officer. Compiles detailed budget from budget owners and facilitates executive management review of functional and consolidated budgets. Tracking Finance responsibilities and timeline for compilation of annual budget and long-term financial plans. Ensures current and multi-year budget & forecast estimates are in line with program strategy timeline and scope. Prepares financial analyses to enable Executive Committee (EC) and Board of Directors (BOD) review and evaluation of annual budgets and proposed transactions. Financial Operations: Review purchase requisitions (PR's) to ensure activity is within budget and Program's operating plan and forecast. Review contractual agreements to ensure they are sound from a financial perspective and optimize the Company's return. Team with other functional areas (Legal, Purchasing, proponents) to facilitate compliance with purchase approval policies through IT systems and manual processes. Execution of responsibilities above requires: Communication, coordination and input from (1) business operations (Clinical Development, Clinical outsourcing & Regulatory) and Program Management and (2) between Accounting and FP&A Understanding and analysis of R&D program requirements, interdependencies and cash payment timing, as well as accounting treatment under GAAP. Skills & Knowledge: Biotech industry experience with clinical trial accounting and/or planning knowledge is required. Previous corporate budgeting and planning experience or accounting experience are required. Excellent project management, analytical, computer and communication (both oral and written) skills are essential. Must be able to demonstrate a high attention to detail with an ability to independently prioritize and organize work/projects/programs. Strong Excel and modeling skills including NPV, IRR and ROI analysis are required. Previous experience with JDE ERP, Business Intelligence reporting software, and Microsoft Access are highly desired. Education & Job Experience: A minimum of a Bachelor's degree in a Finance or Business discipline is required. An advanced degree, such as an MBA, is preferred or equivalent experience may be accepted. A minimum of 8 years previous financial planning experience, preferably in the biotech or pharmaceutical industry is required. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
01/16/2021
Full time
Position Overview Nektar has an exciting opportunity for a Manager, Financial Planning & Analysis to join their Finance & Accounting team. Track and complete compilation of annual budget and long-term financial plans. Key contributor to the annual consolidated budget process. Monitors status compared to budgets and forecasts for the company in total, by program and/or by function. Prepares financial analyses of recurring and non-recurring transactions to enable Finance review. May supervise & direct the activities of the financial planning & analysis staff. Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals. Recommends changes to policies and establishes procedures that affect the immediate organization. Works on issues of diverse scope where analysis of situation or data requires evaluation of a variety of factors, including an understanding of current business trends. Follows processes and operational policies in selecting methods and techniques for obtaining solutions. Develops and administers schedules and performance requirements, may have budget responsibilities. Develop and continually refine corporate performance metrics to aid management in achieving objectives. Ensure clear and effective communication between cross functional groups on matters relating to budgeting, planning, metrics, etc. Responsible for the management of a functional area in the Finance organization. May provide guidance to junior staff within the latitude of established company policies. Acts as advisor to junior staff to meet schedules and/or resolve technical problems. May be responsible for providing regular performance feedback, development and coaching to direct reports. Additionally, the duties and responsibilities of this role entails: Budgeting, forecasting & financial analyses: Oversees and performs the financial requirements for corporate, including: Prepares financial analyses to enable Finance review and evaluation of annual budgets and proposed transactions by Executive Director, Chief Accounting Officer and Chief Financial Officer. Compiles detailed budget from budget owners and facilitates executive management review of functional and consolidated budgets. Tracking Finance responsibilities and timeline for compilation of annual budget and long-term financial plans. Ensures current and multi-year budget & forecast estimates are in line with program strategy timeline and scope. Prepares financial analyses to enable Executive Committee (EC) and Board of Directors (BOD) review and evaluation of annual budgets and proposed transactions. Financial Operations: Review purchase requisitions (PR's) to ensure activity is within budget and Program's operating plan and forecast. Review contractual agreements to ensure they are sound from a financial perspective and optimize the Company's return. Team with other functional areas (Legal, Purchasing, proponents) to facilitate compliance with purchase approval policies through IT systems and manual processes. Execution of responsibilities above requires: Communication, coordination and input from (1) business operations (Clinical Development, Clinical outsourcing & Regulatory) and Program Management and (2) between Accounting and FP&A Understanding and analysis of R&D program requirements, interdependencies and cash payment timing, as well as accounting treatment under GAAP. Skills & Knowledge: Biotech industry experience with clinical trial accounting and/or planning knowledge is required. Previous corporate budgeting and planning experience or accounting experience are required. Excellent project management, analytical, computer and communication (both oral and written) skills are essential. Must be able to demonstrate a high attention to detail with an ability to independently prioritize and organize work/projects/programs. Strong Excel and modeling skills including NPV, IRR and ROI analysis are required. Previous experience with JDE ERP, Business Intelligence reporting software, and Microsoft Access are highly desired. Education & Job Experience: A minimum of a Bachelor's degree in a Finance or Business discipline is required. An advanced degree, such as an MBA, is preferred or equivalent experience may be accepted. A minimum of 8 years previous financial planning experience, preferably in the biotech or pharmaceutical industry is required. We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.