16 jobs found

About Us DLH delivers improved health and national security readiness solutions for federal programs through science research and development, systems engineering and integration, and digital transformation. Our experts in public health, performance evaluation, and health operations solve the complex problems faced by civilian and military customers alike by leveraging advanced tools including digital transformation, artificial intelligence, data analytics, cloud enablement, modeling, and simulation, and more. With over 3,200 employees dedicated to the idea that Your Mission is Our Passion, DLH brings a unique combination of government sector experience, proven methodology, and unwavering commitment to innovation to improve the lives of millions. Overview DLH, a forward-leaning professional technical and engineering services company across Federal, National Security, Intelligence, and Commercial industries, is experiencing steady organic growth. Our next-level solutions and support have earned us national accolades and the trust of our clients for over two decades. With continued growth comes opportunity, and we are currently searching for a Senior Genomic Data Scientist to support our Baltimore, MD office. Position Summary: The Senior Genomic Data Scientist will assist in the creation , security hardening and maintenance of research databases that will directly support the overall function and mission of the National Institute on Aging (NIA). You will combine your understanding of genomic and computational biology knowledge with programming, data warehousing, and quantitative problem solving with data analysis. You will design and implement solutions and corresponding data architectures to address NIA needs. You will work collaboratively with both the IT team and other lab resources to develop a repository of genetic data and the informatics infrastructure in support of the National Institute of Aging research projects while ensuring we adhere to the NIH Genomic Data Sharing Policy. Responsibilities: Develop a data management strategy that integrates all aspects of the organizations Genomic Data. Establish a data governance plan ensuring all data is collected, handled, stored, transported, or shared in accordance with federal mandates, laws and regulations. Ensure all data is tagged and includes all appropriate standardized meta-data attributes and descriptive variables that will be determined in consultation with relevant stakeholders and downstream data consumers. Provide data quality control and assessment . Develop and implement overall quality assurance and quality control (QA/QC) programs or systems covering data coordination and systems management activities critical for the successful operation of the labs. Assist scientists with programming in modern languages such as Java and Python, as well as help to convert legacy codes into massively parallel codes written for GPU using CUDA, RAPIDS or GPU accelerated and/or Python or R programming Works closely with Scientific Director, Clinical Directors, scientific steering committee and others to provide scientific guidance, help define project requirements and monitor project progress. Engineer, maintain, & improve upon pipeline code base for bioinformatics processing & analysis of various genomics data types as well as facilitate internal & external data availability to bioinformaticians and developers. Develop & maintain structured data repositories for semi-automated computational reassessment & record keeping. Interface with research-serving IT specialists to assure availability of appropriate HPC resources (compute, storage, networking) while structuring data storage technologies including relational and/or NoSQL. Other responsibilities not listed Required Qualifications: Degree in Biomedical Sciences, Genomics, Bioinformatics, Molecular Biology, or other healthcare related technical discipline. 8+ years of relevant, applicable professional experience such as but not limited to data management, including data modeling, ontology engineering, metadata management and health data standards. Experience with building repositories, implementation of NIH and NIST policies, and hardening systems using NIH, NIST, and industrial standards. Experience with genomics and bioinformatics with a statistics and statistical analysis of data, machine learning algorithms or general algorithm development and knowledge of molecular biology techniques. Experience with data discovery to take an unknown data set and extract meaningful data, performing data acquisition, data cleansing and other data preparation tasks. Advanced knowledge and expertise in supporting scientific researchers and their specialized systems and equipment with a willingness to stay current with advancements in the genomics field. Experienced software developer with multiple programming languages such as but not limited to R, Python, SAS, MATLAB as well as experience with genomic data analysis tools and software. Very strong interpersonal, problem-solving and analytical skills, customer service, result-oriented, and team-building skills are essential with a strong attention to detail and accuracy. Knowledge of ethical and regulatory standards in genomics research. Experience with laboratory information management systems (LIMS) Desired Skills: Experience supporting a hospital/clinical, governmental, and/or medical research laboratory environment Structuring data storage technologies including relational and/or NoSQL Using version control systems such as Git and/or GitHub, & software project management systems such as Jira. Java, Python, and /or R certification Basic Compensati on: $155,000.00 -$ 170,000.00 yearly salary The salary offered within this range will be based on the selected candidates skills, experience, education, market data, and internal parity. DLH may offer other rewards that may include performance incentives and program-specific awards. An applicants salary history will not be used to determine compensation. Benefits: DLH Corp offers our employees an excellent benefits package including - Personal Time Off (PTO), medical, dental, vision, supplemental life with AD&D, short and long-term disability, flexible spending accounts, parental leave, legal services and more. We want our employees to save for their future, therefore we offer a 401(k) Retirement Plan, which includes a matching component. DLH is dedicated to your career development, providing training to help drive success, with access to our best-in-class e-Learning suite for formal and informal learning, professional and technical certification preparation, and education assistance at accredited institutions. EEO Women, minorities, individuals with disabilities and Veterans are encouraged to apply. DLH Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, pregnancy, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status. DLH will provide a reasonable accommodation to individuals with disabilities and disabled Veterans who need assistance to apply. PIa978c5-

About Allogene Therapeutics, Inc:Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) therapies for cancer. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of off-the-shelf CAR T cell therapy candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit , and on Twitter and LinkedIn.Job Description:Allogene is looking for a seasoned, broadly trained scientist and manager to oversee the external quality Control (QC) testing laboratory operations supporting the CAR T products clinical and commercial manufacturing. Allogene plans to create an outstanding product design, characterization and qualification capability in the allogeneic cell therapy space. The candidate will support the QC organization in ensuring the readiness of QC contract testing laboratories (CTL) for the seamless execution of release and stability testing within agreed upon timeline to meet clinical demands according to plan and budget. The candidate will support the QC head and partner with External Quality Assurance (QA), as well as external partners in defining laboratory systems and processes for the compliant operation of this external QC laboratory network, defining and tracking key performance indicators, and resolving issues as they arise. The candidate will maintain strong connections with the internal Allogene QC laboratories ensuring alignment on requirements for methods, critical reagents, and instruments as needed. The role will entail operating in a fast-paced, highly dynamic environment with company work partnerships including both internal and external stakeholders. This role will report to the Head of QC.Responsibilities include, but are not limited to: Provides leadership, management and technical oversight for the successful execution of release and stability testing at various CTL within agreed upon turnaround-time (TAT) and within budget. Responsible for the review of CTL data, ensuring that they are maintained in compliance with regulatory and Allogenes requirements. Coordinates with Allogene laboratory heads and CTL the maintenance and management of critical laboratory reagents, standards and controls ensuring uninterrupted operation. Establishes processes to trend methods performance at CTL over time. Align with internal Allogene laboratories on control materials and performance as needed. Ensures, where applicable, alignment on instrument requirements/equivalency between Allogene and CTL. Keeps current with revisions to test methods at Allogene and CTL. Where applicable, revises methods and related documentation per established change management procedures at Allogene and CTL. Aligns and coordinates with stability manager on stability samples testing to ensure timely execution and adherence to stability studies schedules. Manages performance of CTL by tracking and ensuring established KPI are met. Escalates CTL performance issues to management in a timely manner. Actively manage CTL associated costs and ensure compliance with budget goals. Oversees validation/verification of methods for CAR T products and raw materials at CTL ensuring compliance with regulatory requirements. Provides direction and guidance to authors of method validations/verifications protocols and reports and evaluate data generated from these activities. Investigates and oversees validation exception reports where needed. In collaboration with Allogene laboratory heads and Head of Infrastructure Support and Methods Life Cycle, oversees technical transfer of CAR T and raw materials methods to and from CTL in line with regulatory requirements and per project timeline and budget. Establishes new and improves existing processes for transfer ensuring cross functional alignment with stakeholders across sites Provides technical guidance and management support for testing related nonconformance events, associated corrective and preventative actions and change control. Collaborates effectively with Allogene External QA to manage the initiation, evaluation, and closure of nonconformance events and CAPA implementation plans at CTL. Investigates unexpected/Out of Specification/Out of Trend test results. Helps define investigation/re-test plans, where applicable. Collaborates effectively with Allogenes and the CTLs QA representatives to manage the initiation, investigation, and compliant closure of these events. Authors and reviews technical registration documents and other sections of regulatory submissions pertaining to methods executed at CTL. Supports Allogene inspections and audits at CTL sites as well as internal Allogene regulatory inspections as the CTL liaison. Supports external QA in ensuring CTL are ready for GMP and pre-approval inspections (PAI). Collaborates cross functionally and builds relationships with external CTL and within Allogene QC, QA, Regulatory Affairs, Development, Manufacturing and Supply Chain to meet target milestones. Be able to negotiate, influence, and work in a matrix environment and across sites. Manages multiple projects, set priorities, and work in a fast-paced environment. Able to negotiate, influence, and work in a matrix environment. Other duties as assignedPosition Requirements & Experience: M.S./B.S. Degree, Ph.D. is a plus. Minimum 6-8 years of analytical development/QC laboratory experience in biotechnology with 2-4 years in a management role. Experience with analytical and biochemical methods including but not limited to cell-based assays/techniques including FACS analysis, potency testing, and immunofluorescence, molecular biology methodologies including but not limited to DNA, RNA manipulation and PCR, ELISA/HTRF, as well as electrophoresis/western blot analysis. Experience with HPLC systems is a plus. Experience with microbiological tests including compendial sterility testing, mycoplasma, endotoxin and viral testing. Strong understanding of GMP requirements and QC systems Experience with method development, validation and transfer Experience in dealing with regulatory agencies, supporting GMP and PAI inspections as well as experience with regulatory filings. Strong leadership ability, interpersonal, communication, and influencing skills required. Highly collaborative with the proven ability to work in a cross-functional team. Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. Ability to work independently and as part of a team. Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment. Expected to travel 15-20% of time. Candidates must be authorized to work in the U.S. Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonablyAs an equal opportunity employer, Allogene Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws.#LI-EL1

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for an Associate Director/Principal Scientist, Virology for our site in Malvern, PA. At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies. The candidate for this position will provide scientific leadership in the area of viral safety and be responsible for driving virology testing programs in raw materials, cell line characterization, unprocessed bulk testing and viral clearance studies to current industry standards and/or best practices. The candidate will provide technical review of external partners protocols, reports, methods, coordinate with and resolve issues with external laboratories and lead activities when required. Candidate may also manage direct reports. Responsibilities also include maintaining an awareness of current issues in viral safety for biopharmaceuticals, authoring technical documents, regulatory filings, supporting quality events and change controls, and contributing to technology transfer to collaboration partners. Responsible as a liaison with manufacturing sites quality control to provide technical oversight for clinical and commercial products. Knowledge of cell and gene therapy manufacturing and testing preferred. The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objectives. The position requires extensive expertise in virology, including familiarity with classical cell culture, nucleic acid testing methods and advanced viral detection systems. Requires substantial communication skills including experience with regulatory agencies, technical writing ability to ensure studies are performed properly and data presented in regulatory documents are understandable to the regulatory community. The candidate will act as a mentor, advisor, and technical subject matter expert to others in the company. Qualifications A PhD in Virology, Microbiology, Biological Sciences or Biochemistry with at least 6 years of relevant business experience OR at least 3 years of experience performing progressively advanced duties at the Senior Scientist level, or equivalent training/ experience is required with a minimum of a bachelor's degree. Knowledge and hands-on experience in cell culture, virology, and nucleic acid methods are required. Knowledge of cell therapy and gene therapy manufacturing, and testing preferred. Experience working in a GMP environment is preferred. CMC regulatory experience is preferred. Experience managing people preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects independently. Good written and verbal communication skills are required. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required. Data reporting, ability to present findings to management, and experience with team-based collaborations is a must. Occasional travel and weekend work may be required. Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Primary Location United States-Pennsylvania-Malvern-200 Great Valley Parkway Organization Janssen Research & Development, LLC (6084) Job Function R&D Requisition ID W

Obsidian Therapeutics is pioneering the development of controllable cell and gene therapies to deliver transformative outcomes for patients with intractable diseases. Obsidian's programs apply our CytoDriveTM technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Our Opportunity… We're looking for a highly motivated scientist with a strong background in cell therapy and/or process development to help drive the development of multiple cell therapy products in our pipeline targeting cancer. As part of our Technical Development and Manufacturing department, you will be a vital part of a highly collaborative team working to achieve Obsidian's vision by translating innovative science into medical breakthroughs for patients. This is a unique opportunity in a well-funded early-stage company with blue-chip investors, field-leading advisors, and a highly experienced team. You will help us build a dynamic, innovative, passionate, collaborative, and successful organization focused on delivering transformative therapies in areas of greatest clinical need. Located in the heart of Cambridge, we're proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. We offer competitive salary and benefits, and potential for employee ownership through stock options. You Will… Contribute your expertise to develop clinical/commercial manufacturing processes, cell therapy products, tech transfer to CDMOs, oversight of external manufacturing, and regulatory filings Drive the design and execution of experiments for development of the cGMP manufacturing process and associate process controls for clinical supply of cell therapy product (and related materials) meeting yield and quality targets Author and review technical and scientific documents including but not limited to study protocols and reports, validation documents, SOPs, and test methods Help build the team, and train and mentor team members on experiment design, data analysis with appropriate scientific rigor and proper documentation in lab notebooks Innovate solutions to address current technical challenges and evaluate/ incorporate next-generation process technologies Supply development materials (viral vector, cell product) to support research/nonclinical studies, analytical development, and CDMO tech transfer activities Lead and support key technology transfer document preparation, technology transfer & implementation of the process, and serve as the technical point of contact for the process development function in assigned projects Establish strong relationships and collaborate closely with internal stakeholders (research, quality, regulatory, project management) Represent process development in CMC sub-teams for assigned projects and support project activities including authoring of relevant CMC sections in regulatory documents You Bring… Core Qualifications Ph.D. and 3+ years of industry experience in a relevant discipline (chemical engineering, biomolecular engineering, biotechnology or relevant field), or MS plus 10 years relevant experience. Subject matter expertise in mammalian cell culture and related aspects such as cell metabolism/media optimization, engineering fundamentals on cell culture scaleup/down, cell biology/physiology Hands-on experience with product characterization methods relevant to cell therapy (e.g. flow cytometry) Highly collaborative working style, and ability to adapt in a fast-paced, rapidly developing environment Ability to work with minimal direction to meet objectives and timelines, adapting to changes and priorities in order to fulfill our mission Bonus Qualifications Prior experience with T-cells, NK cells, induced pluripotent stem cells (iPSC), or other primary cells is a plus. Demonstrated track record with process development supporting early and/or late-stage development of biologics (cell therapy, gene therapy, vaccines, antibodies…) Experience with and technology transfer to CDMOs and external manufacturing oversight Familiar with FDA and EMA guidance documents relevant to gene and cell therapy Experience authoring CMC sections of regulatory documents (IND/BLA) and engaging regulatory authorities Experience with Design of Experiment (DOE) approaches and application to process development Strong working knowledge of cGMP and quality systems requirements Prior experience in managing people and matrixed teams

We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly-growing startup on our mission to translate novel genetic insights into lifesaving medicines. We are integrating human genetics and functional genomics to decode the mysteries of genetic modifiers, leading us to new medicines we'll develop for a range of severe diseases. We are seeking an exceptional, hands-on researcher to join our functional genomics team and contribute to advancing our functional screening for genetic modifiers. The successful candidate will work with Senior Scientist to execute cellular assays and engineer cell models for relevant disease indications. As this team is at the core of our early research, the successful candidate will collaborate with multi-disciplinary scientists for target discovery, being a key contributor generating functional genomics data. The role is hands on in nature and requires a detail-oriented mindset and a curious, motivated disposition to accomplish experiments. Your Role in Navigating The Maze: Design, optimize, and execute cellular assays to enable high throughput functional genomics screening aimed at identifying novel genetic modifier targets. Engineer cell models in disease-relevant systems for hit validation Perform mechanism of action studies, including analysis of protein levels, gene expression, and pathway activity to validate and advance functional genomics targets. Collaborate closely with colleagues on our therapeutic area teams to develop assay strategies for primary screens and secondary assays. Independently summarize, analyze, and regularly present work internally and externally. Contribute to development of automated processes, data analysis methods, and advanced assay technologies. Your Navigation Tools: BS/MS in a Biology related field and at least 3-10 years of relevant experience Broad laboratory experience and skills in molecular and cell biology (DNA/RNA extraction, PCR/qPCR, FACs, NGS library prep, etc.) Expertise in cell-based assay development using a variety of readout technologies such as luciferase, ELISA/immuno-assays, and qPCR/ddPCR gene expression-based assays Expertise in mammalian cell culture is required; experience with genetic perturbation of mammalian cells (CRISPR, RNAi, ASO, lentiviral cell engineering, etc.) is strongly preferred Experience with arrayed screening and comfort with laboratory automation is preferred. Experience with iPSC-derived cell models is a plus Strong experimental design, troubleshooting, and data analysis skills Excellent communication, presentation, collaboration, and organizational skills to work as part of a team. Proven ability to think critically, adapt to new data, multi-task, and work in a fast-paced environment

We are seeking a highly motivated and driven Research Associate who will be key in advancing our preclinical drug development and scientific initiatives. Alkahest's therapeutic focus is on indications impacted by aging, including cognition and disorders of the nervous system. The candidate will help establish in vitro cellular assays to enable bioactive screening and mechanism of action studies centered on the CNS. The candidate will be assisting Alkahest's scientific team to establish, validate, and implement scientific methodologies to understand the biology of our therapeutics at the core of the company's mission. Studies performed will involve cutting edge science and require innovative concepts and strategies. This role requires dedication to drive science, ability to multitask, excellent communication and organizational skills, attention to detail, and the ability to work independently as well as collaboratively with a multidisciplinary team of scientists and research associates to drive multiple projects in parallel in a fast-paced environment. Alkahest offers a competitive compensation and benefits package, opportunities for career growth and development, and a work environment that is collaborative, collegial, and fun. RESPONSIBLITIES: Specific responsibilities include, but are not limited to: Isolating, purifying and maintaining primary neurons, glia and neuronal progenitor cells from mouse Designing, planning, and performing cellular experiments Use of molecular and biochemical analysis methods, immunocytochemistry and microscopy Apply high throughput imaging and analysis techniques Generation and maintenance of stable cell lines Investigating and developing new methods and technologies for project advancement Data analysis and regular presentation of scientific data to the team Maintaining familiarity with current scientific literature Interfacing on a regular basis with lead scientific staff to organize, coordinate, schedule and execute experimental work. Other responsibilities as assigned REQUIREMENTS: Bachelor or Masters degree in biology, cell biology, or neuroscience is required Minimum of five (5) years of progressively advancing responsibilities and technical experience in the lab Experience with immunocytochemistry and microscopy is required Multiple years of experience with primary neuronal tissue culture and cell-based assay development is required Ability to handle and dissect mice to initiate primary cell culture is a must. Experience with other peripheral primary cells, iPSCs and stem cells/progenitor cells or endothelial cell culture systems is a plus Experience with Western Blot, FACS, qPCR and Elisa is a plus Experience with cell-based medium-throughput screening assays is a plus Excellent interpersonal, verbal and written communication skills that enable the individual to interact with all levels of management, technical and scientific personnel Attention to detail and strong organizational skills with the drive for excellence in a high paced environment Solid knowledge of Microsoft Office Suite, microscopy software and analytical packages such as Prism

At Synthetic Genomics, Inc., we are dedicated to developing and commercializing genomic-driven solutions to address global challenges. We are currently seeking a Temporary Research Associate in Biochemistry and Analytical Chemistry to join our dynamic and collaborative team in La Jolla, CA. The Temporary Research Associate will report to a senior scientist and focus on the research and development of novel host production systems for biotechnological applications. The successful candidate will perform biochemical and analytical chemistry work to analyze and evaluate engineered strains of interest. The successful candidate will have practical knowledge of protein biochemistry. Essential Duties & Responsibilities Analytic evaluation of Prokaryotic and Eukaryotic strains in collaboration with other project members. Small scale cultivation of strains including media preparation and culture maintenance. Practical working knowledge of protein biochemistry (protein extraction and analysis, LCMS, GCMS, etc ). Generate detailed and complete notebook and communicate data to group in written and oral reports. Interact effectively within a multidisciplinary team. Requirements Requires a bachelors or Master's degree in Biochemistry, Molecular Biology, Microbiology or a related field with a minimum of 2 years of experience in industry or an academic lab. Basic biochemical and analytical techniques (Protein extraction, SDS-page, Western Blotting, chromatography (LC, GC), enzymatic activity assays, etc ). Proven ability to budget time and manage several distinct projects at once. Eagerness to develop, learn and adopt new methods. Experience working with analytical instrumentation is preferred.

Amgen is a values-based organization with a powerful sense of shared purpose toward our mission: to serve patients. Within Global Commercial Operations, we provide the capabilities, resources, and rewards of a global enterprise, while maintaining the entrepreneurialism and verve that marked our early days as a biotechnology pioneer. We encourage our team members to have fulfilling and meaningful careers through challenging assignments, career development, and valuable opportunities. As part of a new group within Commercial Data and Analytics - Data Sciences, the Data Scientist Sr. Associate will collaborate with business partners, service owners and IS peers to define and manage a capability and technology roadmap for delivering optimized user experience for data consumers across the US Commercial Organization. This role will innovate and create significant business impact through the strategic use of technology and information. This position will help create competitive advantages for Amgen with the ultimate aim to provide clean, usable data to whomever may require it. This position will be primarily responsible for: Ensuring rapid access to new and existing data assets Researching opportunities for data acquisition and new uses for existing data Overseeing end to end data integration and curation including building quality into the process Creating prototypes and demonstrations to better access and utilize data assets Employing a variety of languages and tools (e.g. scripting languages, big data tools) to marry systems together Collaborating cross-functionally with internal partners to ensure a superb user experience throughout the data integration process Managing back-end data configuration Creating data models and solutions architecture in collaboration with IS and external partners Defining processes for managing access to data sets Triaging issues and working with external partners as needed Developing tools and training on data sets and access Collaborating to design, construct, install, test and maintain highly scalable data management systems Ensuring systems meet business requirements and industry best practices Collaborating on definition and implementation of disaster recovery procedures Recommending and implementing ways to improve data reliability, efficiency and quality Collaborating with data architects, modelers and IT team members on project goals Verbally presenting analysis ideas, progress and results to IS peers and business partners. Providing high quality ongoing support; answering questions, resolving problems and building solutions. Assuring compliance with regulatory, security, and privacy requirements as it relates to data assets Serving as an internal consultant on commercial data and data quality management Identifying, recommending and driving continuous improvement in database reporting and analysis processes Basic Qualifications: Master's degree OR Bachelor's degree and 2 years of Data Modeling and/or Data Science and/or Mining and Information Systems experience OR Associate's degree and 6 years of Data Modeling and/or Data Science and/or Mining and Information Systems experience OR High school diploma / GED and 8 years of Data Modeling and/or Data Science and/or Mining and Information Systems experience Preferred Qualifications: Master's Degree in Science, Engineering, Mathematics, Applied Physics, Statistics, or Operations Research 3+ years of relevant work experience Experience with databases Programming experience Detail-oriented technical aptitude with strong logical, problem solving, and decision-making skills. Excellent organization/planning skills and talent for managing many large and complex datasets. Ability to prototype data driven solutions to problems Ability to collaborate with business partners and other IS resources to drive analytic projects end-to-end. Ability to communicate analysis in a clear, precise, and actionable manner. Experience working with large data sets Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Company Description: Molecular Templates is a clinical-stage company focused on the discovery and development of targeted biologic therapeutics. Our proprietary drug platform technology, known as engineered toxin bodies, or ETBs, leverages the resident biology of a genetically engineered form of Shiga-like Toxin A subunit to create novel therapies with potent and differentiated mechanisms of action for cancer and other serious diseases. For more information, please visit MTEM's website at Position Overview: Molecular Templates is seeking an accomplished and highly-motivated Sr. Scientist to join the In Vitro Pharmacology group as part of the research and development (R&D) team. This position will be primarily lab-based and focused on the execution, development and/or refinement of cell-based assays and systems to characterize novel immunotoxins. The Sr. Scientist will contribute to the strategic design of in vitro and in vivo studies and systems to accelerate candidate selection within the R&D pipeline. The Sr. Scientist is expected to work on projects with minimal direct supervision and will be expected to apply good judgment to procedures and choose appropriate approaches to answer outstanding questions. The Sr. Scientist will work closely with more junior team members to train and mentor them and in task delegation. Sr. Scientists will have leadership opportunities managing R&D projects of a larger scope, including both leading technological advancements to the R&D platform as well as early pipeline project leadership. Job Responsibilities will include: Function as the technical leader and point-person for specific techniques within the In Vitro Pharmacology department. Based on methods utilized across industry, develop cell-based assays and experimental systems for use at MTEM to interrogate ETB biology. This includes assay development and validation, SOP generation and training. Effectively communicate high-level biological concepts across departments and to leadership teams. Independently design, execute, and troubleshoot experiments to evaluate activity of novel biologics and ETBs Analyze, draw rational conclusions, and synthesize complex data sets for presentation to team members, external partners, and management in a clear and timely manner. Function as a thought leader to support strategic goals and execution of functional group and project team needs. Maintain knowledge of scientific trends, industry processes and pipeline target literature through readings, conferences, and seminars to contribute to strategic development of novel ETB platforms. Document all procedures in an accurate and timely manner. Conduct general laboratory duties, including ordering supplies and maintaining inventory and laboratory equipment as needed. Manage projects of significant scope, delegate responsibilities, and be accountable for project timelines. Exercise judgment in choosing appropriate experimental approach and in selecting methods, techniques, and evaluation criteria for obtaining desired results to drive projects towards defined goals and milestones. Work independently on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors. Independently mentor junior team members and be responsible for direct reports at the discretion of the management team. Interface with various departments and serves as internal consultant, as needed. May interface with external CROs and collaborators to deliver on project goals. Other duties and responsibilities may be assigned by supervisor, as needed. Qualifications: Master's degree with 7+ years of relevant laboratory experience; or PhD in Biochemistry or related field with 5+ years of relevant laboratory experience. Demonstrated, documented (or directly observed) success in technical proficiency, scientific creativity, collaboration with others and independent thought. Experience in industry R&D, required. Experience with mammalian cell culture, cellular pathway analysis, microscopy techniques, and basic flow cytometry, required Experience with in vitro characterization of biologic drugs in an industry setting, required Track record of project leadership in a drug development setting, preferred Excellent written and verbal communication skills Excellent computer skills with knowledge of spreadsheet, word processing and statistical analysis software Excellent problem-solving and analytical skills applied to investigations Excellent project management, time management, and multi-tasking skills Proven ability to design research projects independently and provide thought-leadership Ability to manage competing priorities or projects and meet deadlines Ability to function independently and exercise good judgement, as well as work closely in cross-functional teams to support multiple pre-clinical stage programs Ability to clearly and efficiently document, communicate and present complex data sets Ability to function in a fast-paced, high-growth and team-based work environment Reporting Structure: This position may have minimal supervisory responsibilities. This position reports to the Director of In Vitro Pharmacology, R&D. Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits. Molecular Templates Inc

Senior Manager / Director, Electrical Engineering Pacific Biosciences of California, Inc. (NASDAQ: PACB) is helping scientists forge a better understanding of biology by providing a unique long-read sequencing technology that generates more complete and accurate data, giving them more insights. Our sequencing systems allow scientists to characterize genomes, transcriptomes, and epigenomes from any organism. Scientists use our technology in areas such as human biomedical research, plant and animal sciences, and microbiology and infectious disease studies. Become part of the new paradigm in long-read sequencing and help shape the future of genomic study by joining the Pacific Biosciences team. Pacific Biosciences is looking for an experienced electrical engineering leader to oversee the development and upkeep of the electronic subsystems for our next generation SMRT sequencing instruments. This person will coordinate a cross disciplinary electrical and FPGA engineering team that is architecting, developing and integrating complex and high-performance subsystems integral to our DNA sequencing products. This person will orchestrate hardware research and development activities related to low level embedded control, high performance sensor data capture and high-performance computing. This successful candidate must have excellent oral and written communication skills and be able to effectively interface with mechanical, optical, software and systems leaders within the department as well as cross departmental leaders in manufacturing and program management. Responsibilities Lead the design and development of the instrument electronics architecture. Work with stakeholders across the company to understand product needs and implement solutions that meet business goals for quality, schedule, and cost. Develop plans and timelines, work with program management to integrate plans into a larger program. Participate in crafting budget for area of responsibility. Transition deliverables to mass production in collaboration with manufacturing NPI. Collaborate with manufacturing on product sustaining activities Select and manage external technology development partners. Attract, develop, and retain an engaged electrical and FPGA engineering team. Requirement Bachelors and/or Masters in Electrical Engineering or related discipline with 10+ years of work experience. Possess an analytical mindset and experience with electronic and FPGA design. Experience managing and architecting complex high performance embedded systems. Demonstrated competency in electronics and computer architecture and transitioning products to manufacturing. Excellent interpersonal, verbal, and written communication skills. Excellent analytical and problem-solving skills, a strong team player, able to take initiative, detail-oriented, and able to work effectively as part of a management team. Thrives in a fast-paced environment, interacting with scientists and engineers from a variety of disciplines. All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

Senior Research Associate I - Antiviral Research United States - California - Foster City Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions. Making an impact on a global scale Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible At Gilead, we strive to transform the promise of science and technology into therapies that have the power to cure, prevent or treat disease. As a research-based biopharmaceutical company, we are revolutionizing healthcare by bringing medicines to patients in the areas of HIV, AIDS, liver diseases, hematology and oncology, and inflammation and respiratory diseases. We are growing a diverse team of professionals and an atmosphere of inclusion across departments. We need your unique talents, expertise and background to help millions of people around the world live healthier. Join a close community where every voice is heard - where you can see and measure the results of your contributions. Our values - integrity, inclusion, teamwork, accountability and excellence - are evident in everything we do. Sr Research Associate - Antiviral Research As a global leader in antiviral therapy, Gilead is committed to the prevention, treatment and cure of many viral infections of global significance. To continue expanding our antiviral research team, we are seeking a highly motivated Senior Research Associate I with experience in virology or related life sciences. The candidate will become an integral part of our team as we work to identify and develop novel agents for the treatment and prevention of major respiratory viral infections. Additionally, the candidate will have unique opportunities to contribute to our collaborative efforts in the discovery and development of new medical countermeasures for emerging and neglected viral pathogens that represent threats to global public health, including building upon Gilead's prior research and current response to coronavirus infections including support of further R&D work on Remdesivir. Key Responsibilities: Perform and optimize various virology and cell biology-based studies to support discovery and development of novel antiviral therapeutics. Design and produce recombinant virus stocks using reverse genetic systems. Analyze and interpret experimental results. Identify of technical issues that may arise in experiments and assist in troubleshooting. Properly document completed experimental methods and results in electronic lab notebooks. Participate in cross-functional group meetings and present results Work closely and collaboratively with team members and senior personnel as a representative of the respiratory and emerging virus group Willingness to work under BSL3 conditions as needed. Gilead is a fast-paced, data-driven, scientifically rigorous organization and the role will suit a scientist who is able to thrive in this type of environment. Knowledge & Skills: Experience with cell culture, RT-qPCR, cloning and sequencing is essential. Knowledge of antiviral assays, virus stock amplification, resistance analysis and ELISA is preferred. Hands-on experience with respiratory viruses (RSV, HRV, SARS-CoV-2) a plus. Desire to learn, implement and troubleshoot new assays. Ability to independently plan and execute experiments that support project goals. Excellent verbal communication and interpersonal skills. Required Qualifications: Bachelor's of Science degree with 2+ years year of experience in Virology, Microbiology, Cell Biology or related life sciences field or Master's of Science degree Molecular biology and lab skills such as cloning, cell culture and qPCR For jobs in the United States: As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance. For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please log onto your Internal Career Site to apply for this job. Copyright ©2017 Jobelephant.com Inc. All rights reserved. Posted by the FREE value-added recruitment advertising agency jeid-0f5adddacabb39b891ed1121

Senior Scientific Recruiter / Scientific Recruiter Pacific Biosciences of California, Inc. (NASDAQ: PACB) is helping scientists forge a better understanding of biology by providing a unique long-read sequencing technology that generates more complete and accurate data, giving them more insights. Our sequencing systems allow scientists to characterize genomes, transcriptomes, and epigenomes from any organism. Scientists use our technology in areas such as human biomedical research, plant and animal sciences, and microbiology and infectious disease studies. Become part of the new paradigm in long-read sequencing and help shape the future of genomic study by joining the PacBio team. Responsibilities: Partners with the business to drive all aspects of the full-cycle recruitment process Prepares for and conducts intake meeting with strong understanding of talent landscape and recommendations for talent strategy Collaborates with Hiring Manager on a complete and logical sourcing strategy/plan Ensures a high level of candidate engagement and positive candidate experience Scheduling of phone screens, interviews, reference checks, and background checks Drives and influences the candidate assessment and selection process with the greater hiring team Offer negotiations and closing of candidates Maintains strong pipeline of qualified candidates and cultivates strong network of passive talent Conducts proactive sourcing of talent using a variety of platforms and approaches Anticipates and proactively communicates recruiting activity and status to Hiring Managers and Business Partners Influence and improves recruiting process and metrics All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities. Requirements: Bachelor's degree with 2+ years of industry experience Experience recruiting scientists and engineers for an R&D organization Experience with Paycor Recruiting (Newton Software) a plus Proficient computer skills and knowledge of Word, Excel, and Outlook Proficient in sourcing techniques including LinkedIn, Google, ATS mining, referrals, etc. Ability to aggressively drive the recruiting process with accuracy and urgency Ability to thrive in a fast-paced, rapidly changing environment Excellent written and verbal communication and interpersonal skills All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

At Lyell, our vision is to develop curative cell-based immunotherapies for solid tumor cancers. We have innovative science originating from our founder's world class labs and a unique and disruptive approach to research and development. Our company is first and foremost focused on understanding the science. We are a learning organization, dependent on deep collaborative relationships between all of our colleagues, partners and founders. Our culture is based on Science, Respect, Courage and Collaboration and it reflects who we are and the environment we are creating. Lyell Immunopharma is seeking a qualified candidate to join our newly established R&D center in South San Francisco and Seattle as a group leader in the TCR team. The ideal candidate will play a principal role in developing the next generation of cancer immunotherapies. The candidate will be responsible for scientifically supporting the TCR team in developing methods to improve antitumor effects of T cells for adoptive cell therapy. Essential Functions: Design and conducts complex experiments independently with scientific rationale. Can critically analyze experiments and interpret complex data drawing appropriate conclusions. Creative thinking, capable to improve the efficiency of current experiments and assays. Communicate and discuss results with other scientists. If a Scientist, represent Lyell externally through presentations at key National / International meetings, interactions with our key investigators. Participate and thrive in an interactive, team-oriented culture. Preferred Experience: Experience with T cell culture and expansion techniques. Deep molecular knowledge and field expertise in T cell biology with a special emphasis in cellular immunotherapy Proven record of relevant experience and expertise in assays involving measurements related to TCR specificity, tumor killing assays, T cell exhaustion, T cell stemness and T cell functionality. Strong cell/molecular biology knowledge and extensive bench experience. Consistent record of innovative contributions to the T cell biology field and/or cancer immunotherapy as evidenced by first / senior-authored publications in top-tier journals and patent authorship (Optional for scientist). Preferred Education: PhD, MSc or BSc degree in molecular biology, cancer biology, immunology, pathology or related field. Preferred Additional Skills: Experience with general T cell culture work (culture, expansion, media formulations, passaging, preservation, co-culture systems. Tumor co-culture assays. Experience with immunohistochemistry, fluorescent microscopy, RT-PCR and Western and Blotting. Experience with cell cytometry and cell sorting. Experience with transcriptional analysis such as RNA-Seq, ATAC-seq and single cell analysis is a plus. At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees. Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws. We've learned from experience that some of the best people don't always match our requirements perfectly - if you're interested and think you could fit, please don't hesitate to apply.

R&D Scientist-La Jolla, CA Volt is seeking a highly motivated individual to support product development efforts within the Genomics organization. This is a hands-on position contributing to nucleic acid isolation-based projects. In this position, you will generate data to demonstrate the performance and effectiveness of manual and automated nucleic acid purification systems. Responsibilities: Perform wet lab bench experiments as directed by senior scientists, primarily focused on manual and automated isolation and purification of nucleic acids from clinical specimens, including those that are potentially-infectious Efficiently manage time to quickly and accurately conduct experiments to meet tight project timelines Perform primary analyses, troubleshoot, and plan next experiments both independently and with consultation from senior scientists, as appropriate Effectively communicate scientific results in both written format and orally at meetings including virtually with colleagues at remote sites Assist senior scientists with lab maintenance, supply, and organizational tasks Meticulously document experiments and verification/validation (V&V) studies Ensure all aspects of lab work, processes, and documentation are performed according to the Quality Management System BS or MS in Molecular Biology or related life science field At least 3-5 years of professional hands-on laboratory experience Experience with nucleic acid chemistry and molecular biology techniques, including troubleshooting and method development Familiar with manual and automated nucleic acid isolation/purification procedures and basic understanding of underlying principles of operation Familiar with nucleic acid quantification, labeling, and detection methods Able to manipulate nucleic acids -- e.g. cloning Versed in QPCR/QRT-PCR and related down-stream nucleic acid detection methodologies; prior experience with DNA sequencing technologies preferred Demonstrated proficiency with standard scientific analysis software and tools Excellent written and oral communication skills Volt is an Equal Opportunity Employer - provided by Dice