Bayer
Cambridge, Massachusetts
At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice. Associate Principal Scientist, Complex in Vitro Expert CVRI Bayer has an opening for an Associate Principal Scientist to join our Cardiovascular-Renal In Vitro Research group based at the Bayer Innovation Campus at the heart of Kendall Square in Cambridge, MA, with the goal to enhance internal expertise in the heart and kidney complex in vitro biology space. We are looking for a scientist with significant hands-on expertise in utilizing advanced cellular models, preferentially 3D organoid systems or organ-on-a-chip, to model cardiac and renal diseases in in vitro settings to enable the characterization of novel drug targets or therapeutic molecules. Specifically, the candidate will design and conduct experimental research studies at the bench, coach research associates, and propose therapeutics project(s) targeting cardiac or renal (including cardio-renal) disease. This is an excellent opportunity for a highly motivated candidate interested in exploring the early stages of drug development in a vibrant and collaborative atmosphere. YOUR TASKS AND RESPONSBILITIES The primary responsibilities of the Associate Principal Scientist - Complex in Vitro Expert CVRI are to: Responsible for identifying and setting up relevant complex in vitro models (3D organoid, organ-on-chip) to support cardiovascular and renal projects from target identification to preclinical candidate acceptance including hands-on experimentation, analysis of data and presentation to cross-functional project teams; Support evaluation of external innovation landscape in the field of complex in vitro models and connection to external partners (CROs, academic partners); Contribute to maintenance of human induced pluripotent stem cell cultures and differentiation into cells of interest (kidney organoids, cardiomyocytes); Establish and provide guidance on QC and analytical protocols to enable a high degree of standardization of assay protocols; Lead novel target proposals and experimental validation to support growth of our early cardiovascular & renal portfolio including presentation at internal governance; Support BD&L assessment of external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration or technological innovation; Engage in close collaboration with scientists and technical staff of the Complex In Vitro Cluster based at the German sites to share knowledge, drive progress and stimulate innovation; Prepare and update experimental protocols; Independently perform data analysis and effectively interpret results; Lead publication of results, prepare reports and presentations at both internal and external forums; Coach research associates in a matrix organization; Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators; Ensure that all tasks are in alignment with respect to HSE guidelines, documentation and good research practices. WHO YOU ARE Bayer seeks an incumbent who possesses the following: Required qualifications: Ph.D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field; Background in cardiorenal disease biology; In depth expertise and hands-on experience in stem cell biology and its translation to cardiovascular or renal disease modeling and drug discovery; Hands-on experience in setting up complex in vitro models (organoids, spheroids, complex co-cultures, organ-on-a-chip) for disease modeling and profiling of drug candidates; Strong expertise in relevant readouts (imaging, flow cytometry, protein and RNA analytical technologies) to characterize complex cellular model systems; Track record of working on complex problems, and ability to integrate data from multiple disciplines; Strong interpersonal, influencing, and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts; Must demonstrate outstanding personal initiative, and accountability, communication skills, and the ability to work effectively as part of a team; Ability to adapt, prioritize activities to and effectively manage changes in a fast paced and dynamic environment; A passion for science and sense of urgency to find new medicines to benefit patients. Preferred qualifications: 4+ years of relevant industrial research experience is preferred with a proven record of successful team leadership and interaction with collaborators. Employees can expect to be paid a salary between 114,846.40 - $172,269.60. Additional compensation may include a bonus or commission (if relevant). Additional benefits include healthcare, vision, dental, retirement, PTO, sick leave, etc. This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, skills, prior relevant experience, certain degrees and certifications, and other relevant factors. This posting will be available for application until at least 12/04/2025. YOUR APPLICATION Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer. To all recruitment agencies: Bayer does not accept unsolicited third party resumes. Bayer is an Equal Opportunity Employer/Disabled/Veterans Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. Bayer is an E-Verify Employer.
At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice. Associate Principal Scientist, Complex in Vitro Expert CVRI Bayer has an opening for an Associate Principal Scientist to join our Cardiovascular-Renal In Vitro Research group based at the Bayer Innovation Campus at the heart of Kendall Square in Cambridge, MA, with the goal to enhance internal expertise in the heart and kidney complex in vitro biology space. We are looking for a scientist with significant hands-on expertise in utilizing advanced cellular models, preferentially 3D organoid systems or organ-on-a-chip, to model cardiac and renal diseases in in vitro settings to enable the characterization of novel drug targets or therapeutic molecules. Specifically, the candidate will design and conduct experimental research studies at the bench, coach research associates, and propose therapeutics project(s) targeting cardiac or renal (including cardio-renal) disease. This is an excellent opportunity for a highly motivated candidate interested in exploring the early stages of drug development in a vibrant and collaborative atmosphere. YOUR TASKS AND RESPONSBILITIES The primary responsibilities of the Associate Principal Scientist - Complex in Vitro Expert CVRI are to: Responsible for identifying and setting up relevant complex in vitro models (3D organoid, organ-on-chip) to support cardiovascular and renal projects from target identification to preclinical candidate acceptance including hands-on experimentation, analysis of data and presentation to cross-functional project teams; Support evaluation of external innovation landscape in the field of complex in vitro models and connection to external partners (CROs, academic partners); Contribute to maintenance of human induced pluripotent stem cell cultures and differentiation into cells of interest (kidney organoids, cardiomyocytes); Establish and provide guidance on QC and analytical protocols to enable a high degree of standardization of assay protocols; Lead novel target proposals and experimental validation to support growth of our early cardiovascular & renal portfolio including presentation at internal governance; Support BD&L assessment of external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration or technological innovation; Engage in close collaboration with scientists and technical staff of the Complex In Vitro Cluster based at the German sites to share knowledge, drive progress and stimulate innovation; Prepare and update experimental protocols; Independently perform data analysis and effectively interpret results; Lead publication of results, prepare reports and presentations at both internal and external forums; Coach research associates in a matrix organization; Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators; Ensure that all tasks are in alignment with respect to HSE guidelines, documentation and good research practices. WHO YOU ARE Bayer seeks an incumbent who possesses the following: Required qualifications: Ph.D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field; Background in cardiorenal disease biology; In depth expertise and hands-on experience in stem cell biology and its translation to cardiovascular or renal disease modeling and drug discovery; Hands-on experience in setting up complex in vitro models (organoids, spheroids, complex co-cultures, organ-on-a-chip) for disease modeling and profiling of drug candidates; Strong expertise in relevant readouts (imaging, flow cytometry, protein and RNA analytical technologies) to characterize complex cellular model systems; Track record of working on complex problems, and ability to integrate data from multiple disciplines; Strong interpersonal, influencing, and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts; Must demonstrate outstanding personal initiative, and accountability, communication skills, and the ability to work effectively as part of a team; Ability to adapt, prioritize activities to and effectively manage changes in a fast paced and dynamic environment; A passion for science and sense of urgency to find new medicines to benefit patients. Preferred qualifications: 4+ years of relevant industrial research experience is preferred with a proven record of successful team leadership and interaction with collaborators. Employees can expect to be paid a salary between 114,846.40 - $172,269.60. Additional compensation may include a bonus or commission (if relevant). Additional benefits include healthcare, vision, dental, retirement, PTO, sick leave, etc. This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, skills, prior relevant experience, certain degrees and certifications, and other relevant factors. This posting will be available for application until at least 12/04/2025. YOUR APPLICATION Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer. To all recruitment agencies: Bayer does not accept unsolicited third party resumes. Bayer is an Equal Opportunity Employer/Disabled/Veterans Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. Bayer is an E-Verify Employer.
Joule
Pittsburgh, Pennsylvania
Title: Mass Spectrometry Senior Scientist Location: Onsite, Pittsburgh, PA 15232 Type: 6-month contract to hire Hours: 8AM-5PM Start: December Overview: Join in establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines, including proteomics, metabolomics, and lipidomics. We are seeking a highly skilled and motivated Senior Scientist for the Mass Spectrometry Facility to oversee day-to-day operations while remaining actively involved in sample processing and instrument analysis. Interested in learning more? Please apply today! Responsibilities Act as the go-to subject matter expert for mass spectrometry, including custom method development, automation initiatives, and troubleshooting to enhance analytical precision and continuous improvements in mass spectrometry-based omics. Ideal candidate should be able to identify erroneous results and execute rapid fault-diagnosis, root-cause identification, and corrective action on mass spectrometers. Perform hands-on work in all aspects of LC-MS/MS workflows, including sample preparation, method development and setup, and data acquisition. Train, mentor, and supervise technical staff; foster a culture of precision, accountability, and teamwork. Collaborate with researchers to design, optimize, and execute mass spectrometry based studies. Ideal candidate should have experience operating, maintaining, calibrating, and troubleshooting mass spectrometers. Maintain accurate records of instrument performance, sample tracking, and results within the Laboratory Information Management System (LIMS). Proven practice in using samples, controls, and standards to create robust reference materials to accurately review and analyze output data. Requirements PhD or Master's degree with 5 years experience in biochemistry, analytical chemistry, or a related field. Minimum of 5 years' experience operating and maintaining mass spectrometers. Preferably 3 + years in a core facility environment working with Thermo Mass Spectrometry instrumentation, with demostrated experience in method development. Proven experience in LC-MS sample preparation, data acquisition, and troubleshooting. Demonstrated ability to manage staff and workflow while maintaining personal engagement in laboratory operations. Strong organizational, problem-solving, and communication skills. A proactive mindset, able to adapt and perform under pressure. Specifically, demonstrate ability to operate in a fast-paced, high-throughput core facility environment. Driven and detail-focused scientist who thrives in a collaborative and high-throughput lab environment. System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. Ref:
Title: Mass Spectrometry Senior Scientist Location: Onsite, Pittsburgh, PA 15232 Type: 6-month contract to hire Hours: 8AM-5PM Start: December Overview: Join in establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines, including proteomics, metabolomics, and lipidomics. We are seeking a highly skilled and motivated Senior Scientist for the Mass Spectrometry Facility to oversee day-to-day operations while remaining actively involved in sample processing and instrument analysis. Interested in learning more? Please apply today! Responsibilities Act as the go-to subject matter expert for mass spectrometry, including custom method development, automation initiatives, and troubleshooting to enhance analytical precision and continuous improvements in mass spectrometry-based omics. Ideal candidate should be able to identify erroneous results and execute rapid fault-diagnosis, root-cause identification, and corrective action on mass spectrometers. Perform hands-on work in all aspects of LC-MS/MS workflows, including sample preparation, method development and setup, and data acquisition. Train, mentor, and supervise technical staff; foster a culture of precision, accountability, and teamwork. Collaborate with researchers to design, optimize, and execute mass spectrometry based studies. Ideal candidate should have experience operating, maintaining, calibrating, and troubleshooting mass spectrometers. Maintain accurate records of instrument performance, sample tracking, and results within the Laboratory Information Management System (LIMS). Proven practice in using samples, controls, and standards to create robust reference materials to accurately review and analyze output data. Requirements PhD or Master's degree with 5 years experience in biochemistry, analytical chemistry, or a related field. Minimum of 5 years' experience operating and maintaining mass spectrometers. Preferably 3 + years in a core facility environment working with Thermo Mass Spectrometry instrumentation, with demostrated experience in method development. Proven experience in LC-MS sample preparation, data acquisition, and troubleshooting. Demonstrated ability to manage staff and workflow while maintaining personal engagement in laboratory operations. Strong organizational, problem-solving, and communication skills. A proactive mindset, able to adapt and perform under pressure. Specifically, demonstrate ability to operate in a fast-paced, high-throughput core facility environment. Driven and detail-focused scientist who thrives in a collaborative and high-throughput lab environment. System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. Ref:
